Author Archives: mhlcc

Nootrobrain | Pure nootropics at the proper dose.

Posted: September 22, 2016 at 7:55 pm

Discover this groundbreaking nootropic cognitive enhancer that delivers improved focus, productivity, speech & memory using 100% pure nootropics at the proper dose.

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How exactly does Nootrobrain work?

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Further, Nootrobrain also improves blood flow to the brain and oxygen uptake by the brain by activating acetylcholine, This activation of acetylcholine uptake and formation is called a cholinergic effect.

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What are the ingredients in Nootrobrain?

Nootrobrain is carefully manufactured in a state of the art facility under the strict guidelines of the U.S. Food and Drug Administrations Good Manufacturing Practices. All ingredients are research-backed, batch tested for purity and included at the real dose used in clinical studies.

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Be heard at First Amendment Field – Longwood University

Posted: at 7:46 pm

In the shadow of a landmark where student activism helped change the world, Longwood University will invite the public to make their voices heard during the Oct. 4 Vice Presidential Debate.

In 1951, 16-year-old Barbara Johns led a student walkout at all-black Moton High School. The students two-week strike launched a court challenge that became part of the Supreme Courts Brown v. Board of Education decision.

Now a National Historic Landmark that is affiliated with Longwood and located a short walk from the debate venue, the Moton Museum will be proud to help welcome a new generation of activists to Farmville on debate day: A field behind the school where Moton students once played will serve as the debates First Amendment Field.

The area will be reserved for public speaking, debate, protest and discussion on the day of the debate. Activists, protestors, concerned citizens and students are invited to address topics important to them from the stage and podium being set up there.

Creating a space for students as well as members of the broader community to engage with the issues they are passionate about… underscores Longwoods commitment to freedom of speech, peaceful protest and civic engagement.

The Moton Museum exists to honor student activism in the civil rights era, said Longwood President W. Taylor Reveley IV. Creating a space for students as well as members of the broader community to engage with the issues they are passionate about, and locating that space next to the museum, underscores Longwoods commitment to freedom of speech, peaceful protest and civic engagement.

The field behind Moton historically has been a site where citizens have asserted their First Amendment rights, said Larissa Fergeson, university liaison to the Moton Museum and professor of history at Longwood. Barbara Johns and her fellow students planned their strike on that field. Fifty years ago, in July 1966, chairman of the Student Nonviolent Coordinating Committee Stokely Carmichael gave a speech to an integrated audience here, a mere month after he coined the term Black Power at a rally in Mississippi.

Longwood University is dedicated to the development of citizen leaders, Reveley said. As the university prepares to be a host once again to history, it was vitally important for us to offer our students and members of the public the opportunity to be heard on the issues that spark their passion.

First Amendment Field is open to the general public from10 a.m.-6 p.m.onOct. 4.Those who wish to speak are strongly encouraged to pre-register for 10-minute time slots via this webpage. Latecomers may register on site if any remaining time slots are available. First Amendment Field will have a stage outfitted with a podium and PA system.

The physical address for First Amendment Field is 800 Griffin Blvd., Farmville, VA. Questions should be directed to Sherry Swinson at swinsonsd@longwood.edu.

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Dolly (sheep) – Wikipedia, the free encyclopedia

Posted: September 18, 2016 at 8:23 am

Dolly (5 July 1996 14 February 2003) was a female domestic sheep, and the first mammal cloned from an adult somatic cell, using the process of nuclear transfer.[2][3] She was cloned by Sir Ian Wilmut, Keith Campbell and colleagues at the Roslin Institute, part of the University of Edinburgh, Scotland, and the biotechnology company PPL Therapeutics, based near Edinburgh. The funding for Dolly’s cloning was provided by PPL Therapeutics and the UK’s Ministry of Agriculture.[4] She was born on 5 July 1996 and died from a progressive lung disease 5 months before her seventh birthday.[5] She has been called “the world’s most famous sheep” by sources including BBC News and Scientific American.[6][7]

The cell used as the donor for the cloning of Dolly was taken from a mammary gland, and the production of a healthy clone therefore proved that a cell taken from a specific part of the body could recreate a whole individual. On Dolly’s name, Wilmut stated “Dolly is derived from a mammary gland cell and we couldn’t think of a more impressive pair of glands than Dolly Parton’s”.[1]

Dolly was born on 5 July 1996 and had three mothers (one provided the egg, another the DNA and a third carried the cloned embryo to term).[8] She was created using the technique of somatic cell nuclear transfer, where the cell nucleus from an adult cell is transferred into an unfertilized oocyte (developing egg cell) that has had its cell nucleus removed. The hybrid cell is then stimulated to divide by an electric shock, and when it develops into a blastocyst it is implanted in a surrogate mother.[9] Dolly was the first clone produced from a cell taken from an adult mammal. The production of Dolly showed that genes in the nucleus of such a mature differentiated somatic cell are still capable of reverting to an embryonic totipotent state, creating a cell that can then go on to develop into any part of an animal.[10] Dolly’s existence was announced to the public on 22 February 1997.[1] It gained much attention in the media. A commercial with Scottish scientists playing with sheep was aired on TV, and a special report in TIME Magazine featured Dolly the sheep.[4]Science featured Dolly as the breakthrough of the year. Even though Dolly was not the first animal cloned, she received media attention because she was the first cloned from an adult cell.[11]

Dolly lived her entire life at the Roslin Institute in Edinburgh. There she was bred with a Welsh Mountain ram and produced six lambs in total. Her first lamb, named Bonnie, was born in April 1998.[5] The next year Dolly produced twin lambs Sally and Rosie, and she gave birth to triplets Lucy, Darcy and Cotton in the year after that.[12] In late 2001, at the age of four, Dolly developed arthritis and began to walk stiffly. This was treated with anti-inflammatory drugs.[13]

On 14 February 2003, Dolly was euthanised because she had a progressive lung disease and severe arthritis.[14] A Finn Dorset such as Dolly has a life expectancy of around 11 to 12 years, but Dolly lived 6.5 years. A post-mortem examination showed she had a form of lung cancer called Jaagsiekte,[15] which is a fairly common disease of sheep and is caused by the retrovirus JSRV.[16] Roslin scientists stated that they did not think there was a connection with Dolly being a clone, and that other sheep in the same flock had died of the same disease.[14] Such lung diseases are a particular danger for sheep kept indoors, and Dolly had to sleep inside for security reasons.

Some in the press speculated that a contributing factor to Dolly’s death was that she could have been born with a genetic age of six years, the same age as the sheep from which she was cloned.[17] One basis for this idea was the finding that Dolly’s telomeres were short, which is typically a result of the aging process.[18][19] The Roslin Institute stated that intensive health screening did not reveal any abnormalities in Dolly that could have come from advanced aging.[17]

In 2016 scientists reported no defects in thirteen cloned sheep, including four from the same cell line as Dolly. The first study to review the long-term health outcomes of cloning, the authors found no evidence of late-onset, non-communicable diseases other than some minor examples of oseteoarthritis and concluded “We could find no evidence, therefore, of a detrimental long-term effect of cloning by SCNT on the health of aged offspring among our cohort.”[20][21]

After cloning was successfully demonstrated through the production of Dolly, many other large mammals were cloned, including pigs,[22][23]deer,[24]horses[25] and bulls.[26] The attempt to clone argali (mountain sheep) did not produce viable embryos. The attempt to clone a banteng bull was more successful, as were the attempts to clone mouflon (a form of wild sheep), both resulting in viable offspring.[27] The reprogramming process cells need to go through during cloning is not perfect and embryos produced by nuclear transfer often show abnormal development.[28][29] Making cloned mammals was highly inefficient in 1996 Dolly was the only lamb that survived to adulthood from 277 attempts. However, by 2014 Chinese scientists were reported to have 7080% success rates cloning pigs[23] and in 2016, a Korean company, Sooam Biotech was producing 500 cloned embryos a day.[30] Wilmut, who led the team that created Dolly, announced in 2007 that the nuclear transfer technique may never be sufficiently efficient for use in humans.[31]

Cloning may have uses in preserving endangered species and may become a viable tool for reviving extinct species.[32] In January 2009, scientists from the Centre of Food Technology and Research of Aragon, in northern Spain announced the cloning of the Pyrenean ibex, a form of wild mountain goat, which was officially declared extinct in 2000. Although the newborn ibex died shortly after birth due to physical defects in its lungs, it is the first time an extinct animal has been cloned, and may open doors for saving endangered and newly extinct species by resurrecting them from frozen tissue.[33][34]

In July, 2016, four identical clones of the Dolly sheep (Daisy, Debbie, Dianna and Denise) were alive and healthy at nine years old.[35][36]

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Congressional report slams NSA leaker Edward Snowden

Posted: at 8:12 am

WASHINGTON A House intelligence committee report issued Thursday condemned Edward Snowden, saying the National Security Agency leaker is not a whistleblower and that the vast majority of the documents he stole were defense secrets that had nothing to do with privacy.

The Republican-led committee released a three-page unclassified summary of its two-year bipartisan examination of howSnowdenwas able to remove more than 1.5 million classified documents from secure NSA networks, what the documents contained and the damage their removal caused to U.S. national security.

Snowdenwas an NSA contract employee when he took the documents and leaked them to journalists who revealed massive domestic surveillance programs begun in the aftermath of the 9/11 attacks. The programs collected the telephone metadata records of millions of Americans and examined emails from overseas.Snowdenfled to Hong Kong, then Russia, to avoid prosecution and now wants a presidential pardon as a whistleblower.

Rep. Devin Nunes, R-Calif., chairman of the committee, saidSnowdenbetrayed his colleagues and his country.

“He put our service members and the American people at risk after perceived slights by his superiors,” Nunes said in a statement. “In light of his long list of exaggerations and outright fabrications detailed in this report, no one should take him at his word. I look forward to his eventual return to the United States, where he will face justice for his damaging crimes.”

Snowdeninsists he has not shared the full cache of 1.5 million classified documents with anyone. However, the report notes that in June, the deputy chairman of the Russian parliament’s defense and security committee publicly conceded that “Snowdendid share intelligence” with his government.

Ben Wizner,Snowden’sattorney at the American Civil Liberties Union, blasted the report, saying it was an attempt to discredit a “genuine American hero.”

“After years of investigation, the committee still can’t point to any remotely credible evidence that Snowden’sdisclosures caused harm,” Wizner said. “In a more candid moment, the NSA’s former deputy director, who was directly involved in the government’s investigation, explicitly said he didn’t believe Snowdenhad cooperated with either China or Russia.”

Snowden’srevelations about the agency’s bulk collection of millions of Americans’ phone records set off a fierce debate that pit civil libertarians concerned about privacy against more hawkish lawmakers fearful about losing tools to combat terrorism. Democrats and libertarian-leaning Republicans pushed through a reauthorization of the USA Patriot Act last year that ended the program.

There was little evidence that the phone records or other surveillance programsSnowdenrevealed ever thwarted an attack.

Snowdenis seeking a presidential pardon because he says he helped his country by revealing secret domestic surveillance programs. Separately, all members of the committee sent a bipartisan letter to President Barack Obama urging him not to pardonSnowden.

“The vast majority of what he took has nothing to do with American privacy,” said Rep. Adam Schiff of California, the ranking Democrat on the House intelligence committee.

“The majority of what he took has to do with military secrets and defense secrets,” Schiff said in an interview Thursday for C-SPAN’s “Newsmakers.” ”I think that’s very much at odds with the narrative that he wants to tell that he is a whistleblower.”

The Obama administration has urgedSnowdento return to the U.S. and face trial. Justice Department spokesman Marc Raimondi has said “there is no question his actions have inflicted serious harms on our national security.”

The committee report says that he was a “disgruntled employee who had frequent conflicts with his managers.”

Publicly revealing classified information does not qualify someone as a whistleblower, the report said. The committee “found no evidence thatSnowdentook any official effort to express concerns about U.S. intelligence activities to any oversight officials within the U.S. government, despite numerous avenues for him to do so.”

According to the committee,Snowdenbegan mass downloads of classified material two weeks after he was reprimanded for engaging in a spat with NSA managers. The committee also describedSnowdenas a “serial exaggerator and fabricator.”

“A close review ofSnowden’sofficial employment records and submissions reveals a pattern of intentional lying,” the report said. “He claimed to have left Army basic training because of broken legs when in fact he washed out because of shin splints. He claimed to have obtained a high school degree equivalent when in fact he never did. ”

The report saidSnowdenclaimed to have worked for the CIA as a senior adviser, when he was a computer technician.

“He also doctored his performance evaluations and obtained new positions at NSA by exaggerating his resume and stealing the answers to an employment test,” the report said.

Speaking by video link from Moscow,Snowdensaid Wednesday that whistleblowing “is democracy’s safeguard of last resort, the one on which we rely when all other checks and balances have failed and the public has no idea what’s going on behind closed doors.”

The 33-year-old addressed a New York City news conference where advocates from the American Civil Liberties Union, Human Rights Watch and Amnesty International announced an online petition drive to urge Obama to pardonSnowdenbefore he leaves office. The supporters calledSnowdena hero for exposing the extent of government surveillance by giving thousands of classified documents to journalists.

The report was released one day ahead of Friday’s opening of director Oliver Stone’s film “Snowden.”

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Psoriasis | DermNet New Zealand

Posted: at 8:09 am

Home Topics AZ Psoriasis

Author:Hon A/Prof Amanda Oakley, Hamilton, New Zealand. Revised and updated, August 2014.

Psoriasis is a chronic inflammatory skin condition characterised by clearly defined, red and scaly plaques (thickened skin). It is classified into several subtypes.

Psoriasis affects 24% of males and females. It can start at any age including childhood, with peaks of onset at 1525 years and 5060 years. It tends to persist lifelong, fluctuating in extent and severity. It is particularly common in Caucasians, but may affect people of any race. About one third of patients with psoriasis have family members with psoriasis.

Psoriasis is multifactorial. It is classified as an immune-mediated inflammatory disease (IMID).

Genetic factors are important. An individual’s genetic profile influences their type of psoriasis and its response to treatment.

Genome-wide association studies report that HLA-Cw6 is associated with early onset psoriasis and guttate psoriasis. This major histocompatibility complex is not associated with arthritis, nail dystrophy or late onset psoriasis.

Theories about the causes of psoriasis need to explain why the skin is red, inflamed and thickened. It is clear that immune factors and inflammatory cytokines (messenger proteins) such is IL1 and TNF are responsible for the clinical features of psoriasis. Current theories are exploring the TH17 pathway and release of the cytokine IL17A.

Psoriasis usually presents with symmetrically distributed, red, scaly plaques with well-defined edges. The scale is typically silvery white, except in skin folds where the plaques often appear shiny and they may have a moist peeling surface. The most common sites are scalp, elbows and knees, but any part of the skin can be involved. The plaques are usually very persistent without treatment.

Itch is mostly mild but may be severe in some patients, leading to scratching and lichenification (thickened leathery skin with increased skin markings). Painful skin cracks or fissures may occur.

When psoriatic plaques clear up, they may leave brown or pale marks that can be expected to fade over several months.

Certain features of psoriasis can be categorised to help determine appropriate investigations and treatment pathways. Overlap may occur.

Generalised pustulosis and localised palmoplantar pustulosis are no longer classified within the psoriasis spectrum.

Patients with psoriasis are more likely than other people to have other health conditions listed here.

Psoriasis is diagnosed by its clinical features. If necessary, diagnosis is supported by typical skin biopsy findings.

Medical assessment entails a careful history, examination, questioning about effect of psoriasis on daily life, and evaluation of comorbid factors.

Validated tools used to evaluate psoriasis include:

The severity of psoriasis is classified as mild in 60% of patients, moderate in 30% and severe in 10%.

Evaluation of comorbidities may include:

Patients with psoriasis should ensure they are well informed about their skin condition and its treatment. There are benefits from not smoking, avoiding excessive alcohol and maintaining optimal weight.

Mild psoriasis is generally treated with topical agents alone. Which treatment is selected may depend on body site, extent and severity of the psoriasis.

Most psoriasis centres offer phototherapy with ultraviolet (UV) radiation, often in combination with topical or systemic agents. Types of phototherapy include

Moderate to severe psoriasis warrants treatment with a systemic agent and/or phototherapy. The most common treatments are:

Other medicines occasionally used for psoriasis include:

Systemic corticosteroids are best avoided due to risk of severe withdrawal flare of psoriasis and adverse effects.

Biologics or targeted therapies are reserved for conventional treatment-resistant severe psoriasis, mainly because of expense, as side effects compare favourably with other systemic agents. These include:

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THE ABOLITION OF WORK by Bob Black

Posted: September 16, 2016 at 5:26 am

No one should ever work.

Work is the source of nearly all the misery in the world. Almost any evil you’d care to name comes from working or from living in a world designed for work. In order to stop suffering, we have to stop working.

That doesn’t mean we have to stop doing things. It does mean creating a new way of life based on play; in other words, a ludic conviviality, commensality, and maybe even art. There is more to play than child’s play, as worthy as that is. I call for a collective adventure in generalized joy and freely interdependent exuberance. Play isn’t passive. Doubtless we all need a lot more time for sheer sloth and slack than we ever enjoy now, regardless of income or occupation, but once recovered from employment-induced exhaustion nearly all of us want to act. Oblomovism and Stakhanovism are two sides of the same debased coin.

The ludic life is totally incompatible with existing reality. So much the worse for “reality,” the gravity hole that sucks the vitality from the little in life that still distinguishes it from mere survival. Curiously — or maybe not — all the old ideologies are conservative because they believe in work. Some of them, like Marxism and most brands of anarchism, believe in work all the more fiercely because they believe in so little else.

Liberals say we should end employment discrimination. I say we should end employment. Conservatives support right-to-work laws. Following Karl Marx’s wayward son-in-law Paul Lafargue I support the right to be lazy. Leftists favor full employment. Like the surrealists — except that I’m not kidding — I favor full unemployment. Trotskyists agitate for permanent revolution. I agitate for permanent revelry. But if all the ideologues (as they do) advocate work — and not only because they plan to make other people do theirs — they are strangely reluctant to say so. They will carry on endlessly about wages, hours, working conditions, exploitation, productivity, profitability. They’ll gladly talk about anything but work itself. These experts who offer to do our thinking for us rarely share their conclusions about work, for all its saliency in the lives of all of us. Among themselves they quibble over the details. Unions and management agree that we ought to sell the time of our lives in exchange for survival, although they haggle over the price. Marxists think we should be bossed by bureaucrats. Libertarians think we should be bossed by businessmen. Feminists don’t care which form bossing takes so long as the bosses are women. Clearly these ideology-mongers have serious differences over how to divvy up the spoils of power. Just as clearly, none of them have any objection to power as such and all of them want to keep us working.

You may be wondering if I’m joking or serious. I’m joking and serious. To be ludic is not to be ludicrous. Play doesn’t have to be frivolous, although frivolity isn’t triviality: very often we ought to take frivolity seriously. I’d like life to be a game — but a game with high stakes. I want to play for keeps.

The alternative to work isn’t just idleness. To be ludic is not to be quaaludic. As much as I treasure the pleasure of torpor, it’s never more rewarding than when it punctuates other pleasures and pastimes. Nor am I promoting the managed time-disciplined safety-valve called “leisure”; far from it. Leisure is nonwork for the sake of work. Leisure is the time spent recovering from work and in the frenzied but hopeless attempt to forget about work. Many people return from vacation so beat that they look forward to returning to work so they can rest up. The main difference between work and leisure is that work at least you get paid for your alienation and enervation.

I am not playing definitional games with anybody. When I say I want to abolish work, I mean just what I say, but I want to say what I mean by defining my terms in non-idiosyncratic ways. My minimum definition of work is forced labor, that is, compulsory production. Both elements are essential. Work is production enforced by economic or political means, by the carrot or the stick. (The carrot is just the stick by other means.) But not all creation is work. Work is never done for its own sake, it’s done on account of some product or output that the worker (or, more often, somebody else) gets out of it. This is what work necessarily is. To define it is to despise it. But work is usually even worse than its definition decrees. The dynamic of domination intrinsic to work tends over time toward elaboration. In advanced work-riddled societies, including all industrial societies whether capitalist of “Communist,” work invariably acquires other attributes which accentuate its obnoxiousness.

Usually — and this is even more true in “Communist” than capitalist countries, where the state is almost the only employer and everyone is an employee — work is employment, i. e., wage-labor, which means selling yourself on the installment plan. Thus 95% of Americans who work, work for somebody (or something) else. In the USSR or Cuba or Yugoslavia or any other alternative model which might be adduced, the corresponding figure approaches 100%. Only the embattled Third World peasant bastions — Mexico, India, Brazil, Turkey — temporarily shelter significant concentrations of agriculturists who perpetuate the traditional arrangement of most laborers in the last several millenia, the payment of taxes (= ransom) to the state or rent to parasitic landlords in return for being otherwise left alone. Even this raw deal is beginning to look good. All industrial (and office) workers are employees and under the sort of surveillance which ensures servility.

But modern work has worse implications. People don’t just work, they have “jobs.” One person does one productive task all the time on an or-else basis. Even if the task has a quantum of intrinsic interest (as increasingly many jobs don’t) the monotony of its obligatory exclusivity drains its ludic potential. A “job” that might engage the energies of some people, for a reasonably limited time, for the fun of it, is just a burden on those who have to do it for forty hours a week with no say in how it should be done, for the profit of owners who contribute nothing to the project, and with no opportunity for sharing tasks or spreading the work among those who actually have to do it. This is the real world of work: a world of bureaucratic blundering, of sexual harassment and discrimination, of bonehead bosses exploiting and scapegoating their subordinates who — by any rational-technical criteria — should be calling the shots. But capitalism in the real world subordinates the rational maximization of productivity and profit to the exigencies of organizational control.

The degradation which most workers experience on the job is the sum of assorted indignities which can be denominated as “discipline.” Foucault has complexified this phenomenon but it is simple enough. Discipline consists of the totality of totalitarian controls at the workplace — surveillance, rotework, imposed work tempos, production quotas, punching -in and -out, etc. Discipline is what the factory and the office and the store share with the prison and the school and the mental hospital. It is something historically original and horrible. It was beyond the capacities of such demonic dictators of yore as Nero and Genghis Khan and Ivan the Terrible. For all their bad intentions they just didn’t have the machinery to control their subjects as thoroughly as modern despots do. Discipline is the distinctively diabolical modern mode of control, it is an innovative intrusion which must be interdicted at the earliest opportunity.

Such is “work.” Play is just the opposite. Play is always voluntary. What might otherwise be play is work if it’s forced. This is axiomatic. Bernie de Koven has defined play as the “suspension of consequences.” This is unacceptable if it implies that play is inconsequential. The point is not that play is without consequences. This is to demean play. The point is that the consequences, if any, are gratuitous. Playing and giving are closely related, they are the behavioral and transactional facets of the same impulse, the play-instinct. They share an aristocratic disdain for results. The player gets something out of playing; that’s why he plays. But the core reward is the experience of the activity itself (whatever it is). Some otherwise attentive students of play, like Johan Huizinga (Homo Ludens), define it as game-playing or following rules. I respect Huizinga’s erudition but emphatically reject his constraints. There are many good games (chess, baseball, Monopoly, bridge) which are rule-governed but there is much more to play than game-playing. Conversation, sex, dancing, travel — these practices aren’t rule-governed but they are surely play if anything is. And rules can be played with at least as readily as anything else.

Work makes a mockery of freedom. The official line is that we all have rights and live in a democracy. Other unfortunates who aren’t free like we are have to live in police states. These victims obey orders or-else, no matter how arbitrary. The authorities keep them under regular surveillance. State bureaucrats control even the smaller details of everyday life. The officials who push them around are answerable only to higher-ups, public or private. Either way, dissent and disobedience are punished. Informers report regularly to the authorities. All this is supposed to be a very bad thing.

And so it is, although it is nothing but a description of the modern workplace. The liberals and conservatives and libertarians who lament totalitarianism are phonies and hypocrites. There is more freedom in any moderately deStalinized dictatorship than there is in the ordinary American workplace. You find the same sort of hierarchy and discipline in an office or factory as you do in a prison or monastery. In fact, as Foucault and others have shown, prisons and factories came in at about the same time, and their operators consciously borrowed from each other’s control techniques. A worker is a part time slave. The boss says when to show up, when to leave, and what to do in the meantime. He tells you how much work to do and how fast. He is free to carry his control to humiliating extremes, regulating, if he feels like it, the clothes you wear or how often you go to the bathroom. With a few exceptions he can fire you for any reason, or no reason. He has you spied on by snitches and supervisors, he amasses a dossier on every employee. Talking back is called “insubordination,” just as if a worker is a naughty child, and it not only gets you fired, it disqualifies you for unemployment compensation. Without necessarily endorsing it for them either, it is noteworthy that children at home and in school receive much the same treatment, justified in their case by their supposed immaturity. What does this say about their parents and teachers who work?

The demeaning system of domination I’ve described rules over half the waking hours of a majority of women and the vast majority of men for decades, for most of their lifespans. For certain purposes it’s not too misleading to call our system democracy or capitalism or — better still — industrialism, but its real names are factory fascism and office oligarchy. Anybody who says these people are “free” is lying or stupid. You are what you do. If you do boring, stupid monotonous work, chances are you’ll end up boring, stupid and monotonous. Work is a much better explanation for the creeping cretinization all around us than even such significant moronizing mechanisms as television and education. People who are regimented all their lives, handed off to work from school and bracketed by the family in the beginning and the nursing home at the end, are habituated to heirarchy and psychologically enslaved. Their aptitude for autonomy is so atrophied that their fear of freedom is among their few rationally grounded phobias. Their obedience training at work carries over into the families they start, thus reproducing the system in more ways than one, and into politics, culture and everything else. Once you drain the vitality from people at work, they’ll likely submit to heirarchy and expertise in everything. They’re used to it.

We are so close to the world of work that we can’t see what it does to us. We have to rely on outside observers from other times or other cultures to appreciate the extremity and the pathology of our present position. There was a time in our own past when the “work ethic” would have been incomprehensible, and perhaps Weber was on to something when he tied its appearance to a religion, Calvinism, which if it emerged today instead of four centuries ago would immediately and appropriately be labeled a cult. Be that as it may, we have only to draw upon the wisdom of antiquity to put work in perspective. The ancients saw work for what it is, and their view prevailed, the Calvinist cranks notwithstanding, until overthrown by industrialism — but not before receiving the endorsement of its prophets.

Let’s pretend for a moment that work doesn’t turn people into stultified submissives. Let’s pretend, in defiance of any plausible psychology and the ideology of its boosters, that it has no effect on the formation of character. And let’s pretend that work isn’t as boring and tiring and humiliating as we all know it really is. Even then, work would still make a mockery of all humanistic and democratic aspirations, just because it usurps so much of our time. Socrates said that manual laborers make bad friends and bad citizens because they have no time to fulfill the responsibilities of friendship and citizenship. He was right. Because of work, no matter what we do we keep looking at our watches. The only thing “free” about so-called free time is that it doesn’t cost the boss anything. Free time is mostly devoted to getting ready for work, going to work, returning from work, and recovering from work. Free time is a euphemism for the peculiar way labor as a factor of production not only transports itself at its own expense to and from the workplace but assumes primary responsibility for its own maintenance and repair. Coal and steel don’t do that. Lathes and typewriters don’t do that. But workers do. No wonder Edward G. Robinson in one of his gangster movies exclaimed, “Work is for saps!”

Both Plato and Xenophon attribute to Socrates and obviously share with him an awareness of the destructive effects of work on the worker as a citizen and a human being. Herodotus identified contempt for work as an attribute of the classical Greeks at the zenith of their culture. To take only one Roman example, Cicero said that “whoever gives his labor for money sells himself and puts himself in the rank of slaves.” His candor is now rare, but contemporary primitive societies which we are wont to look down upon have provided spokesmen who have enlightened Western anthropologists. The Kapauku of West Irian, according to Posposil, have a conception of balance in life and accordingly work only every other day, the day of rest designed “to regain the lost power and health.” Our ancestors, even as late as the eighteenth century when they were far along the path to our present predicament, at least were aware of what we have forgotten, the underside of industrialization. Their religious devotion to “St. Monday” — thus establishing a de facto five-day week 150-200 years before its legal consecration — was the despair of the earliest factory owners. They took a long time in submitting to the tyranny of the bell, predecessor of the time clock. In fact it was necessary for a generation or two to replace adult males with women accustomed to obedience and children who could be molded to fit industrial needs. Even the exploited peasants of the ancient regime wrested substantial time back from their landlord’s work. According to Lafargue, a fourth of the French peasants’ calendar was devoted to Sundays and holidays, and Chayanov’s figures from villages in Czarist Russia — hardly a progressive society — likewise show a fourth or fifth of peasants’ days devoted to repose. Controlling for productivity, we are obviously far behind these backward societies. The exploited muzhiks would wonder why any of us are working at all. So should we.

To grasp the full enormity of our deterioration, however, consider the earliest condition of humanity, without government or property, when we wandered as hunter-gatherers. Hobbes surmised that life was then nasty, brutish and short. Others assume that life was a desperate unremitting struggle for subsistence, a war waged against a harsh Nature with death and disaster awaiting the unlucky or anyone who was unequal to the challenge of the struggle for existence. Actually, that was all a projection of fears for the collapse of government authority over communities unaccustomed to doing without it, like the England of Hobbes during the Civil War. Hobbes’ compatriots had already encountered alternative forms of society which illustrated other ways of life — in North America, particularly — but already these were too remote from their experience to be understandable. (The lower orders, closer to the condition of the Indians, understood it better and often found it attractive. Throughout the seventeenth century, English settlers defected to Indian tribes or, captured in war, refused to return. But the Indians no more defected to white settlements than Germans climb the Berlin Wall from the west.) The “survival of the fittest” version — the Thomas Huxley version — of Darwinism was a better account of economic conditions in Victorian England than it was of natural selection, as the anarchist Kropotkin showed in his book Mutual Aid, A Factor of Evolution. (Kropotkin was a scientist — a geographer — who’d had ample involuntary opportunity for fieldwork whilst exiled in Siberia: he knew what he was talking about.) Like most social and political theory, the story Hobbes and his successors told was really unacknowledged autobiography.

The anthropologist Marshall Sahlins, surveying the data on contemporary hunter-gatherers, exploded the Hobbesian myth in an article entitled “The Original Affluent Society.” They work a lot less than we do, and their work is hard to distinguish from what we regard as play. Sahlins concluded that “hunters and gatherers work less than we do; and rather than a continuous travail, the food quest is intermittent, leisure abundant, and there is a greater amount of sleep in the daytime per capita per year than in any other condition of society.” They worked an average of four hours a day, assuming they were “working” at all. Their “labor,” as it appears to us, was skilled labor which exercised their physical and intellectual capacities; unskilled labor on any large scale, as Sahlins says, is impossible except under industrialism. Thus it satisfied Friedrich Schiller’s definition of play, the only occasion on which man realizes his complete humanity by giving full “play” to both sides of his twofold nature, thinking and feeling. As he put it: “The animal works when deprivation is the mainspring of its activity, and it plays when the fullness of its strength is this mainspring, when superabundant life is its own stimulus to activity.” (A modern version — dubiously developmental — is Abraham Maslow’s counterposition of “deficiency” and “growth” motivation.) Play and freedom are, as regards production, coextensive. Even Marx, who belongs (for all his good intentions) in the productivist pantheon, observed that “the realm of freedom does not commence until the point is passed where labor under the compulsion of necessity and external utility is required.” He never could quite bring himself to identify this happy circumstance as what it is, the abolition of work — it’s rather anomalous, after all, to be pro-worker and anti-work — but we can.

The aspiration to go backwards or forwards to a life without work is evident in every serious social or cultural history of pre-industrial Europe, among them M. Dorothy George’s England In Transition and Peter Burke’s Popular Culture in Early Modern Europe. Also pertinent is Daniel Bell’s essay, “Work and its Discontents,” the first text, I believe, to refer to the “revolt against work” in so many words and, had it been understood, an important correction to the complacency ordinarily associated with the volume in which it was collected, The End of Ideology. Neither critics nor celebrants have noticed that Bell’s end-of-ideology thesis signaled not the end of social unrest but the beginning of a new, uncharted phase unconstrained and uninformed by ideology. It was Seymour Lipset (in Political Man), not Bell, who announced at the same time that “the fundamental problems of the Industrial Revolution have been solved,” only a few years before the post- or meta-industrial discontents of college students drove Lipset from UC Berkeley to the relative (and temporary) tranquility of Harvard.

As Bell notes, Adam Smith in The Wealth of Nations, for all his enthusiasm for the market and the division of labor, was more alert to (and more honest about) the seamy side of work than Ayn Rand or the Chicago economists or any of Smith’s modern epigones. As Smith observed: “The understandings of the greater part of men are necessarily formed by their ordinary employments. The man whose life is spent in performing a few simple operations… has no occasion to exert his understanding… He generally becomes as stupid and ignorant as it is possible for a human creature to become.” Here, in a few blunt words, is my critique of work. Bell, writing in 1956, the Golden Age of Eisenhower imbecility and American self-satisfaction, identified the unorganized, unorganizable malaise of the 1970’s and since, the one no political tendency is able to harness, the one identified in HEW’s report Work in America, the one which cannot be exploited and so is ignored. That problem is the revolt against work. It does not figure in any text by any laissez-faire economist — Milton Friedman, Murray Rothbard, Richard Posner — because, in their terms, as they used to say on Star Trek, “it does not compute.”

If these objections, informed by the love of liberty, fail to persuade humanists of a utilitarian or even paternalist turn, there are others which they cannot disregard. Work is hazardous to your health, to borrow a book title. In fact, work is mass murder or genocide. Directly or indirectly, work will kill most of the people who read these words. Between 14,000 and 25,000 workers are killed annually in this country on the job. Over two million are disabled. Twenty to twenty-five million are injured every year. And these figures are based on a very conservative estimation of what constitutes a work-related injury. Thus they don’t count the half million cases of occupational disease every year. I looked at one medical textbook on occupational diseases which was 1,200 pages long. Even this barely scratches the surface. The available statistics count the obvious cases like the 100,000 miners who have black lung disease, of whom 4,000 die every year, a much higher fatality rate than for AIDS, for instance, which gets so much media attention. This reflects the unvoiced assumption that AIDS afflicts perverts who could control their depravity whereas coal-mining is a sacrosanct activity beyond question. What the statistics don’t show is that tens of millions of people have heir lifespans shortened by work — which is all that homicide means, after all. Consider the doctors who work themselves to death in their 50’s. Consider all the other workaholics.

Even if you aren’t killed or crippled while actually working, you very well might be while going to work, coming from work, looking for work, or trying to forget about work. The vast majority of victims of the automobile are either doing one of these work-obligatory activities or else fall afoul of those who do them. To this augmented body-count must be added the victims of auto-industrial pollution and work-induced alcoholism and drug addiction. Both cancer and heart disease are modern afflictions normally traceable, directly, or indirectly, to work.

Work, then, institutionalizes homicide as a way of life. People think the Cambodians were crazy for exterminating themselves, but are we any different? The Pol Pot regime at least had a vision, however blurred, of an egalitarian society. We kill people in the six-figure range (at least) in order to sell Big Macs and Cadillacs to the survivors. Our forty or fifty thousand annual highway fatalities are victims, not martyrs. They died for nothing — or rather, they died for work. But work is nothing to die for.

Bad news for liberals: regulatory tinkering is useless in this life-and-death context. The federal Occupational Safety and Health Administration was designed to police the core part of the problem, workplace safety. Even before Reagan and the Supreme Court stifled it, OSHA was a farce. At previous and (by current standards) generous Carter-era funding levels, a workplace could expect a random visit from an OSHA inspector once every 46 years.

State control of the economy is no solution. Work is, if anything, more dangerous in the state-socialist countries than it is here. Thousands of Russian workers were killed or injured building the Moscow subway. Stories reverberate about covered-up Soviet nuclear disasters which make Times Beach and Three-Mile Island look like elementary-school air-raid drills. On the other hand, deregulation, currently fashionable, won’t help and will probably hurt. From a health and safety standpoint, among others, work was at its worst in the days when the economy most closely approximated laissez-faire.

Historians like Eugene Genovese have argued persuasively that — as antebellum slavery apologists insisted — factory wage-workers in the Northern American states and in Europe were worse off than Southern plantation slaves. No rearrangement of relations among bureaucrats and businessmen seems to make much difference at the point of production. Serious enforcement of even the rather vague standards enforceable in theory by OSHA would probably bring the economy to a standstill. The enforcers apparently appreciate this, since they don’t even try to crack down on most malefactors.

What I’ve said so far ought not to be controversial. Many workers are fed up with work. There are high and rising rates of absenteeism, turnover, employee theft and sabotage, wildcat strikes, and overall goldbricking on the job. There may be some movement toward a conscious and not just visceral rejection of work. And yet the prevalent feeling, universal among bosses and their agents and also widespread among workers themselves is that work itself is inevitable and necessary.

I disagree. It is now possible to abolish work and replace it, insofar as it serves useful purposes, with a multitude of new kinds of free activities. To abolish work requires going at it from two directions, quantitative and qualitative. On the one hand, on the quantitative side, we have to cut down massively on the amount of work being done. At present most work is useless or worse and we should simply get rid of it. On the other hand — and I think this is the crux of the matter and the revolutionary new departure — we have to take what useful work remains and transform it into a pleasing variety of game-like and craft-like pastimes, indistinguishable from other pleasurable pastimes, except that they happen to yield useful end-products. Surely that shouldn’t make them less enticing to do. Then all the artificial barriers of power and property could come down. Creation could become recreation. And we could all stop being afraid of each other.

I don’t suggest that most work is salvageable in this way. But then most work isn’t worth trying to save. Only a small and diminishing fraction of work serves any useful purpose independent of the defense and reproduction of the work-system and its political and legal appendages. Twenty years ago, Paul and Percival Goodman estimated that just five percent of the work then being done — presumably the figure, if accurate, is lower now — would satisfy our minimal needs for food, clothing, and shelter. Theirs was only an educated guess but the main point is quite clear: directly or indirectly, most work serves the unproductive purposes of commerce or social control. Right off the bat we can liberate tens of millions of salesmen, soldiers, managers, cops, stockbrokers, clergymen, bankers, lawyers, teachers, landlords, security guards, ad-men and everyone who works for them. There is a snowball effect since every time you idle some bigshot you liberate his flunkeys and underlings also. Thus the economy implodes.

Forty percent of the workforce are white-collar workers, most of whom have some of the most tedious and idiotic jobs ever concocted. Entire industries, insurance and banking and real estate for instance, consist of nothing but useless paper-shuffling. It is no accident that the “tertiary sector,” the service sector, is growing while the “secondary sector” (industry) stagnates and the “primary sector” (agriculture) nearly disappears. Because work is unnecessary except to those whose power it secures, workers are shifted from relatively useful to relatively useless occupations as a measure to assure public order. Anything is better than nothing. That’s why you can’t go home just because you finish early. They want your time, enough of it to make you theirs, even if they have no use for most of it. Otherwise why hasn’t the average work week gone down by more than a few minutes in the past fifty years?

Next we can take a meat-cleaver to production work itself. No more war production, nuclear power, junk food, feminine hygiene deodorant — and above all, no more auto industry to speak of. An occasional Stanley Steamer or Model-T might be all right, but the auto-eroticism on which such pestholes as Detroit and Los Angeles depend on is out of the question. Already, without even trying, we’ve virtually solved the energy crisis, the environmental crisis and assorted other insoluble social problems.

Finally, we must do away with far and away the largest occupation, the one with the longest hours, the lowest pay and some of the most tedious tasks around. I refer to housewives doing housework and child-rearing. By abolishing wage-labor and achieving full unemployment we undermine the sexual division of labor. The nuclear family as we know it is an inevitable adaptation to the division of labor imposed by modern wage-work. Like it or not, as things have been for the last century or two it is economically rational for the man to bring home the bacon, for the woman to do the shitwork to provide him with a haven in a heartless world, and for the children to be marched off to youth concentration camps called “schools,” primarily to keep them out of Mom’s hair but still under control, but incidentally to acquire the habits of obedience and punctuality so necessary for workers. If you would be rid of patriarchy, get rid of the nuclear family whose unpaid “shadow work,” as Ivan Illich says, makes possible the work-system that makes it necessary. Bound up with this no-nukes strategy is the abolition of childhood and the closing of the schools. There are more full-time students than full-time workers in this country. We need children as teachers, not students. They have a lot to contribute to the ludic revolution because they’re better at playing than grown-ups are. Adults and children are not identical but they will become equal through interdependence. Only play can bridge the generation gap.

I haven’t as yet even mentioned the possibility of cutting way down on the little work that remains by automating and cybernizing it. All the scientists and engineers and technicians freed from bothering with war research and planned obsolescence would have a good time devising means to eliminate fatigue and tedium and danger from activities like mining. Undoubtedly they’ll find other projects to amuse themselves with. Perhaps they’ll set up world-wide all-inclusive multi-media communications systems or found space colonies. Perhaps. I myself am no gadget freak. I wouldn’t care to live in a pushbutton paradise. I don’t want robot slaves to do everything; I want to do things myself. There is, I think, a place for labor-saving technology, but a modest place. The historical and pre-historical record is not encouraging. When productive technology went from hunting-gathering to agriculture and on to industry, work increased while skills and self-determination diminished. The further evolution of industrialism has accentuated what Harry Braverman called the degradation of work. Intelligent observers have always been aware of this. John Stuart Mill wrote that all the labor-saving inventions ever devised haven’t saved a moment’s labor. Karl Marx wrote that “it would be possible to write a history of the inventions, made since 1830, for the sole purpose of supplying capital with weapons against the revolts of the working class.” The enthusiastic technophiles — Saint-Simon, Comte, Lenin, B. F. Skinner — have always been unabashed authoritarians also; which is to say, technocrats. We should be more than sceptical about the promises of the computer mystics. They work like dogs; chances are, if they have their way, so will the rest of us. But if they have any particularized contributions more readily subordinated to human purposes than the run of high tech, let’s give them a hearing.

What I really want to see is work turned into play. A first step is to discard the notions of a “job” and an “occupation.” Even activities that already have some ludic content lose most of it by being reduced to jobs which certain people, and only those people are forced to do to the exclusion of all else. Is it not odd that farm workers toil painfully in the fields while their air-conditioned masters go home every weekend and putter about in their gardens? Under a system of permanent revelry, we will witness the Golden Age of the dilettante which will put the Renaissance to shame. There won’t be any more jobs, just things to do and people to do them.

The secret of turning work into play, as Charles Fourier demonstrated, is to arrange useful activities to take advantage of whatever it is that various people at various times in fact enjoy doing. To make it possible for some people to do the things they could enjoy it will be enough just to eradicate the irrationalities and distortions which afflict these activities when they are reduced to work. I, for instance, would enjoy doing some (not too much) teaching, but I don’t want coerced students and I don’t care to suck up to pathetic pedants for tenure.

Second, there are some things that people like to do from time to time, but not for too long, and certainly not all the time. You might enjoy baby-sitting for a few hours in order to share the company of kids, but not as much as their parents do. The parents meanwhile, profoundly appreciate the time to themselves that you free up for them, although they’d get fretful if parted from their progeny for too long. These differences among individuals are what make a life of free play possible. The same principle applies to many other areas of activity, especially the primal ones. Thus many people enjoy cooking when they can practice it seriously at their leisure, but not when they’re just fueling up human bodies for work.

Third — other things being equal — some things that are unsatisfying if done by yourself or in unpleasant surroundings or at the orders of an overlord are enjoyable, at least for a while, if these circumstances are changed. This is probably true, to some extent, of all work. People deploy their otherwise wasted ingenuity to make a game of the least inviting drudge-jobs as best they can. Activities that appeal to some people don’t always appeal to all others, but everyone at least potentially has a variety of interests and an interest in variety. As the saying goes, “anything once.” Fourier was the master at speculating how aberrant and perverse penchants could be put to use in post-civilized society, what he called Harmony. He thought the Emperor Nero would have turned out all right if as a child he could have indulged his taste for bloodshed by working in a slaughterhouse. Small children who notoriously relish wallowing in filth could be organized in “Little Hordes” to clean toilets and empty the garbage, with medals awarded to the outstanding. I am not arguing for these precise examples but for the underlying principle, which I think makes perfect sense as one dimension of an overall revolutionary transformation. Bear in mind that we don’t have to take today’s work just as we find it and match it up with the proper people, some of whom would have to be perverse indeed. If technology has a role in all this it is less to automate work out of existence than to open up new realms for re/creation. To some extent we may want to return to handicrafts, which William Morris considered a probable and desirable upshot of communist revolution. Art would be taken back from the snobs and collectors, abolished as a specialized department catering to an elite audience, and its qualities of beauty and creation restored to integral life from which they were stolen by work. It’s a sobering thought that the grecian urns we write odes about and showcase in museums were used in their own time to store olive oil. I doubt our everyday artifacts will fare as well in the future, if there is one. The point is that there’s no such thing as progress in the world of work; if anything it’s just the opposite. We shouldn’t hesitate to pilfer the past for what it has to offer, the ancients lose nothing yet we are enriched.

The reinvention of daily life means marching off the edge of our maps. There is, it is true, more suggestive speculation than most people suspect. Besides Fourier and Morris — and even a hint, here and there, in Marx — there are the writings of Kropotkin, the syndicalists Pataud and Pouget, anarcho-communists old (Berkman) and new (Bookchin). The Goodman brothers’ Communitas is exemplary for illustrating what forms follow from given functions (purposes), and there is something to be gleaned from the often hazy heralds of alternative/appropriate/intermediate/convivial technology, like Schumacher and especially Illich, once you disconnect their fog machines. The situationists — as represented by Vaneigem’s Revolution of Daily Life and in the Situationist International Anthology — are so ruthlessly lucid as to be exhilarating, even if they never did quite square the endorsement of the rule of the worker’s councils with the abolition of work. Better their incongruity, though than any extant version of leftism, whose devotees look to be the last champions of work, for if there were no work there would be no workers, and without workers, who would the left have to organize?

So the abolitionists would be largely on their own. No one can say what would result from unleashing the creative power stultified by work. Anything can happen. The tiresome debater’s problem of freedom vs. necessity, with its theological overtones, resolves itself practically once the production of use-values is coextensive with the consumption of delightful play-activity.

Life will become a game, or rather many games, but not — as it is now – — a zero/sum game. An optimal sexual encounter is the paradigm of productive play, The participants potentiate each other’s pleasures, nobody keeps score, and everybody wins. The more you give, the more you get. In the ludic life, the best of sex will diffuse into the better part of daily life. Generalized play leads to the libidinization of life. Sex, in turn, can become less urgent and desperate, more playful. If we play our cards right, we can all get more out of life than we put into it; but only if we play for keeps.

No one should ever work. Workers of the world… relax!

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THE ABOLITION OF WORK by Bob Black

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DNA – Definition by AcronymFinder

Posted: September 14, 2016 at 1:08 am

DNA Department(al) Network Administrator DNA Does Not Apply DNA Deoxyribonucleic Acid DNA Genentech, Inc (stock symbol) DNA Data Not Available DNA Dermatology Nurses’ Association DNA Directia Nationala Anticoruptie (Romanian) DNA Defense Nuclear Agency DNA Do Not Adopt (used by animal shelters to refer to animal abusers) DNA Det Norske Arbeiderparti (Norwegian Labour Party) DNA Distributed Internet Applications Architecture (Microsoft) DNA Dynamic Network Administration (Ericsson) DNA De Nieuw Amsterdam (theater group) DNA Distributed Network Attack DNA Do Not Announce (hospital patient privacy) DnA Do Not Abbreviate (online gaming clan) DNA Deutscher Normenausschuss (German Committee of Standards) DNA National Dyslexia Association (humor) DNA Direct Network Access DNA Dernire Nouvelles d’Alsace (French newspaper) DNA DoNotAge (OSPF) DNA Datanetwork Associates (Software) DNA Dinebeiina Nahiilna be Agaditahe (Navajo legal counselors) DNA Did Not Answer DNA Did Not Attend DNA Do Not Ask DNA Definitely Not Attractive DNA Down Auxiliary DNA Distributed Internetwork Architecture (Microsoft) DNA Did Not Attack (Dana Carvey) DNA Do Not Approve DNA Do Not Answer (cell phone) DNA Do Not Admit DNA Drug ‘n Alcohol (band) DNA Diversified Naval Architects, Inc. (Ottawa, Ontario, Canada) DNA Dorchester Neighborhood Association (Waldorf, Maryland) DNA Djibouti National Army DNA Digital Narrowband Analysis DNA Distributed Networking Agent DNA Downriver Numismatic Association DNA Designated National Authority DNA Douglas Noel Adams (late British author of the Hitchhiker’s Guide to the Galaxy series) DNA Development Needs Analysis DNA Digital Network Architecture DNA Digital Nonlinear Accelerator DNA Direction de la Navigation Arienne (French: Directorate of Air Navigation; Morocco) DNA Direction Nationale de l’Arbitrage (French: National Directorate of Arbitration) DNA Direzione Nazionale Antimafia (Italian: National Anti-Mafia Directorate) DNA Distributed interNet Applications DNA Detroit News Agency DNA Die Neue Allianz (German: The New Alliance) DNA Dernires Nouvelles d’Algrie (French: Latest News from Algeria) DNA Department of Native Affairs (various locations) DNA Dpense Non Admise (French: Non-Deductible Expense) DNA Delaware Nurses Association DNA Delayed Neutron Activation DNA Delivery Network Accelerator (BitTorrent) DNA Delta Nu Alpha DNA Denver Newspaper Agency (Denver, CO) DNA Daily News and Analysis (India; newspaper) DNA Dark Native Apostle (gaming) DNA Domain Name Authority (various locations) DNA Doctors Net Access DNA Distribution Nationale Airsoft (French airsoft supply company) DNA Distributed Network Analyzer DNA Do Not Abbreviate DNA Dynamic Network Analyzer (Lucent) DNA Dynamic Network Architecture

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DNA – Definition by AcronymFinder

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Sealand Wikipedia ting Vit

Posted: September 11, 2016 at 5:31 pm

Thn vng quc Sealand (ting Anh: Principality of Sealand) l mt vi quc gia khng c Lin Hip Quc cng nhn, nm pha ng Anh Quc, cch o Anh 10 hi l. Sealand l mt pho i (l ct) c xy dng nm 1942 phc v cho chin tranh th gii th 2. C th gi Sealand l mt hn o hoc mt “quc gia” c bit. Gi l o bi v n c xy dng gia bin ng vng bng hai chn trn bin. Gi l quc gia bi v ti y cng c quc k, quc ca, c tng thng v cc hot ng thng mi cng nh lut php ca mnh.

Sau khi Chin tranh th gii th 2 kt thc, qun i Anh rt khi hn o ny. N c b hoang cho n nm 1967, khi Roy pht hin ra n. Roy t t ra mt quc gia v t gi mnh l Hong t, gi v mnh l Cng cha. Roy t mnh thit k ra c, tin t,… Sealand tr thnh ci gai trong mt Chnh ph Anh, nhng h khng th lm g c v Sealand thuc hi phn quc t. Cc cng ty truyn thng t cc my ch ca mnh ti Sealand, l tr tt c cc thng tin ca mnh ti y. Bn ti phm cng li dng s s h phc v cho hot ng phm php ca chng. Roy cng nhn ra iu ny, v thit k h chiu gim hot ng ca ti phm.

Thn vng quc Sealand l mt trong nhng lnh th khng c Lin Hip Quc cng nhn.

Sealand vn l mt n lnh trn bin cch Suffolk, Anh 10 km v pha ng. T ngy 2 thng 10 nm 1967, n b chim gi bi gia nh k thut vin Paddy Roy Bates. Thy qun Hong gia Anh tng tn cng Sealand nhng v n nm ngoi lnh hi Anh cho nn vic lm b ngn chn.

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Cloning Fact Sheet

Posted: at 5:26 pm

Cloning What is cloning?

The term cloning describes a number of different processes that can be used to produce genetically identical copies of a biological entity. The copied material, which has the same genetic makeup as the original, is referred to as a clone.

Researchers have cloned a wide range of biological materials, including genes, cells, tissues and even entire organisms, such as a sheep.

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Yes. In nature, some plants and single-celled organisms, such as bacteria, produce genetically identical offspring through a process called asexual reproduction. In asexual reproduction, a new individual is generated from a copy of a single cell from the parent organism.

Natural clones, also known as identical twins, occur in humans and other mammals. These twins are produced when a fertilized egg splits, creating two or more embryos that carry almost identical DNA. Identical twins have nearly the same genetic makeup as each other, but they are genetically different from either parent.

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There are three different types of artificial cloning: gene cloning, reproductive cloning and therapeutic cloning.

Gene cloning produces copies of genes or segments of DNA. Reproductive cloning produces copies of whole animals. Therapeutic cloning produces embryonic stem cells for experiments aimed at creating tissues to replace injured or diseased tissues.

Gene cloning, also known as DNA cloning, is a very different process from reproductive and therapeutic cloning. Reproductive and therapeutic cloning share many of the same techniques, but are done for different purposes.

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Gene cloning is the most common type of cloning done by researchers at the National Human Genome Research Institute (NHGRI). NHGRI researchers have not cloned any mammals and NHGRI does not clone humans.

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Researchers routinely use cloning techniques to make copies of genes that they wish to study. The procedure consists of inserting a gene from one organism, often referred to as “foreign DNA,” into the genetic material of a carrier called a vector. Examples of vectors include bacteria, yeast cells, viruses or plasmids, which are small DNA circles carried by bacteria. After the gene is inserted, the vector is placed in laboratory conditions that prompt it to multiply, resulting in the gene being copied many times over.

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In reproductive cloning, researchers remove a mature somatic cell, such as a skin cell, from an animal that they wish to copy. They then transfer the DNA of the donor animal’s somatic cell into an egg cell, or oocyte, that has had its own DNA-containing nucleus removed.

Researchers can add the DNA from the somatic cell to the empty egg in two different ways. In the first method, they remove the DNA-containing nucleus of the somatic cell with a needle and inject it into the empty egg. In the second approach, they use an electrical current to fuse the entire somatic cell with the empty egg.

In both processes, the egg is allowed to develop into an early-stage embryo in the test-tube and then is implanted into the womb of an adult female animal.

ltimately, the adult female gives birth to an animal that has the same genetic make up as the animal that donated the somatic cell. This young animal is referred to as a clone. Reproductive cloning may require the use of a surrogate mother to allow development of the cloned embryo, as was the case for the most famous cloned organism, Dolly the sheep.

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Over the last 50 years, scientists have conducted cloning experiments in a wide range of animals using a variety of techniques. In 1979, researchers produced the first genetically identical mice by splitting mouse embryos in the test tube and then implanting the resulting embryos into the wombs of adult female mice. Shortly after that, researchers produced the first genetically identical cows, sheep and chickens by transferring the nucleus of a cell taken from an early embryo into an egg that had been emptied of its nucleus.

It was not until 1996, however, that researchers succeeded in cloning the first mammal from a mature (somatic) cell taken from an adult animal. After 276 attempts, Scottish researchers finally produced Dolly, the lamb from the udder cell of a 6-year-old sheep. Two years later, researchers in Japan cloned eight calves from a single cow, but only four survived.

Besides cattle and sheep, other mammals that have been cloned from somatic cells include: cat, deer, dog, horse, mule, ox, rabbit and rat. In addition, a rhesus monkey has been cloned by embryo splitting.

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Despite several highly publicized claims, human cloning still appears to be fiction. There currently is no solid scientific evidence that anyone has cloned human embryos.

In 1998, scientists in South Korea claimed to have successfully cloned a human embryo, but said the experiment was interrupted very early when the clone was just a group of four cells. In 2002, Clonaid, part of a religious group that believes humans were created by extraterrestrials, held a news conference to announce the birth of what it claimed to be the first cloned human, a girl named Eve. However, despite repeated requests by the research community and the news media, Clonaid never provided any evidence to confirm the existence of this clone or the other 12 human clones it purportedly created.

In 2004, a group led by Woo-Suk Hwang of Seoul National University in South Korea published a paper in the journal Science in which it claimed to have created a cloned human embryo in a test tube. However, an independent scientific committee later found no proof to support the claim and, in January 2006, Science announced that Hwang’s paper had been retracted.

From a technical perspective, cloning humans and other primates is more difficult than in other mammals. One reason is that two proteins essential to cell division, known as spindle proteins, are located very close to the chromosomes in primate eggs. Consequently, removal of the egg’s nucleus to make room for the donor nucleus also removes the spindle proteins, interfering with cell division. In other mammals, such as cats, rabbits and mice, the two spindle proteins are spread throughout the egg. So, removal of the egg’s nucleus does not result in loss of spindle proteins. In addition, some dyes and the ultraviolet light used to remove the egg’s nucleus can damage the primate cell and prevent it from growing.

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No. Clones do not always look identical. Although clones share the same genetic material, the environment also plays a big role in how an organism turns out.

For example, the first cat to be cloned, named Cc, is a female calico cat that looks very different from her mother. The explanation for the difference is that the color and pattern of the coats of cats cannot be attributed exclusively to genes. A biological phenomenon involving inactivation of the X chromosome (See sex chromosome) in every cell of the female cat (which has two X chromosomes) determines which coat color genes are switched off and which are switched on. The distribution of X inactivation, which seems to occur randomly, determines the appearance of the cat’s coat.

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Reproductive cloning may enable researchers to make copies of animals with the potential benefits for the fields of medicine and agriculture.

For instance, the same Scottish researchers who cloned Dolly have cloned other sheep that have been genetically modified to produce milk that contains a human protein essential for blood clotting. The hope is that someday this protein can be purified from the milk and given to humans whose blood does not clot properly. Another possible use of cloned animals is for testing new drugs and treatment strategies. The great advantage of using cloned animals for drug testing is that they are all genetically identical, which means their responses to the drugs should be uniform rather than variable as seen in animals with different genetic make-ups.

After consulting with many independent scientists and experts in cloning, the U.S. Food and Drug Administration (FDA) decided in January 2008 that meat and milk from cloned animals, such as cattle, pigs and goats, are as safe as those from non-cloned animals. The FDA action means that researchers are now free to using cloning methods to make copies of animals with desirable agricultural traits, such as high milk production or lean meat. However, because cloning is still very expensive, it will likely take many years until food products from cloned animals actually appear in supermarkets.

Another application is to create clones to build populations of endangered, or possibly even extinct, species of animals. In 2001, researchers produced the first clone of an endangered species: a type of Asian ox known as a guar. Sadly, the baby guar, which had developed inside a surrogate cow mother, died just a few days after its birth. In 2003, another endangered type of ox, called the Banteg, was successfully cloned. Soon after, three African wildcats were cloned using frozen embryos as a source of DNA. Although some experts think cloning can save many species that would otherwise disappear, others argue that cloning produces a population of genetically identical individuals that lack the genetic variability necessary for species survival.

Some people also have expressed interest in having their deceased pets cloned in the hope of getting a similar animal to replace the dead one. But as shown by Cc the cloned cat, a clone may not turn out exactly like the original pet whose DNA was used to make the clone.

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Reproductive cloning is a very inefficient technique and most cloned animal embryos cannot develop into healthy individuals. For instance, Dolly was the only clone to be born live out of a total of 277 cloned embryos. This very low efficiency, combined with safety concerns, presents a serious obstacle to the application of reproductive cloning.

Researchers have observed some adverse health effects in sheep and other mammals that have been cloned. These include an increase in birth size and a variety of defects in vital organs, such as the liver, brain and heart. Other consequences include premature aging and problems with the immune system. Another potential problem centers on the relative age of the cloned cell’s chromosomes. As cells go through their normal rounds of division, the tips of the chromosomes, called telomeres, shrink. Over time, the telomeres become so short that the cell can no longer divide and, consequently, the cell dies. This is part of the natural aging process that seems to happen in all cell types. As a consequence, clones created from a cell taken from an adult might have chromosomes that are already shorter than normal, which may condemn the clones’ cells to a shorter life span. Indeed, Dolly, who was cloned from the cell of a 6-year-old sheep, had chromosomes that were shorter than those of other sheep her age. Dolly died when she was six years old, about half the average sheep’s 12-year lifespan.

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Therapeutic cloning involves creating a cloned embryo for the sole purpose of producing embryonic stem cells with the same DNA as the donor cell. These stem cells can be used in experiments aimed at understanding disease and developing new treatments for disease. To date, there is no evidence that human embryos have been produced for therapeutic cloning.

The richest source of embryonic stem cells is tissue formed during the first five days after the egg has started to divide. At this stage of development, called the blastocyst, the embryo consists of a cluster of about 100 cells that can become any cell type. Stem cells are harvested from cloned embryos at this stage of development, resulting in destruction of the embryo while it is still in the test tube.

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Researchers hope to use embryonic stem cells, which have the unique ability to generate virtually all types of cells in an organism, to grow healthy tissues in the laboratory that can be used replace injured or diseased tissues. In addition, it may be possible to learn more about the molecular causes of disease by studying embryonic stem cell lines from cloned embryos derived from the cells of animals or humans with different diseases. Finally, differentiated tissues derived from ES cells are excellent tools to test new therapeutic drugs.

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Many researchers think it is worthwhile to explore the use of embryonic stem cells as a path for treating human diseases. However, some experts are concerned about the striking similarities between stem cells and cancer cells. Both cell types have the ability to proliferate indefinitely and some studies show that after 60 cycles of cell division, stem cells can accumulate mutations that could lead to cancer. Therefore, the relationship between stem cells and cancer cells needs to be more clearly understood if stem cells are to be used to treat human disease.

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Gene cloning is a carefully regulated technique that is largely accepted today and used routinely in many labs worldwide. However, both reproductive and therapeutic cloning raise important ethical issues, especially as related to the potential use of these techniques in humans.

Reproductive cloning would present the potential of creating a human that is genetically identical to another person who has previously existed or who still exists. This may conflict with long-standing religious and societal values about human dignity, possibly infringing upon principles of individual freedom, identity and autonomy. However, some argue that reproductive cloning could help sterile couples fulfill their dream of parenthood. Others see human cloning as a way to avoid passing on a deleterious gene that runs in the family without having to undergo embryo screening or embryo selection.

Therapeutic cloning, while offering the potential for treating humans suffering from disease or injury, would require the destruction of human embryos in the test tube. Consequently, opponents argue that using this technique to collect embryonic stem cells is wrong, regardless of whether such cells are used to benefit sick or injured people.

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Last Reviewed: May 11, 2016

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Alternative Medicine | What Is Alternative Medicine?

Posted: at 5:25 pm

Alternative medicine is becoming ever increasingly popular in this day and age, but what exactly is alternative medicine? It takes on many forms in a wide variety of guises from remedies such as Herbs, Oils, Massage and Chinese Acupuncture, which most of us will have heard of and maybe even tried to Ayurvedic medicine which has widely been used in India for over five thousand years.Alternative medicine was once perhaps given a wide berth by the sceptics but today over 600 million people pay visits to those offering alternative treatments and remedies. What Benefit does Alternative Medicine Have?

Most alternative treatments are based on the use of herbs, oils and massage so its perfectly safe and for thousands of people it has been proven to work time and time again. There are a vast array of different types and treatments available from minor illnesses through to those more severe, some people even suffering life threatening illnesses have benefited from some types of alternative medicine where conventional treatments have failed.

Listed below are some of the types of alternative treatments and therapies available:

Acupuncture treatment is not only the insertion of fine needles into the points on the body but also the detection of disharmony within the body. This is assessed by a series of questions on the persons lifestyle and emotions.

Originating from the Chinese Taoist monks acupressure is similar to acupuncture but without the use of needles, instead finger pressure is applied to the points.

Essential oils taken from plants are used in this treatment which can take the form of massage or inhalation. It is thought to be especially beneficial for those suffering from stress related illnesses.

This type of treatment stems back from India and is a complete system of exercise, diet and detoxification of the entire body.

Chiropractic treatment works mainly for those suffering from joint problems and is performed along the spine by adjusting joints.

There is a vast range of herbs used in treatment which the Chinese have used for thousands of years and are capable of treating a wide variety of illnesses.

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Alternative Medicine | What Is Alternative Medicine?

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