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Category Archives: Cf

Real Madrid CF slump to loss vs Valencia CF in La Liga – Hindustan Times

Posted: February 26, 2017 at 11:22 pm

Real Madrid C.F., after their loss to Valencia C.F., are just a single point clear of Barcelona and three points ahead of Sevilla and now enjoy just one game in hand over their title rivals

Two goals in the opening eight minutes from Simone Zaza and Fabian Orellana blew the La Liga title race wide open as Valencia beat leaders Real Madrid 2-1 on Wednesday.

The defeat leaves Madrid just a single point clear of Barcelona and three points ahead of Sevilla and now enjoy just one game in hand over their title rivals.

We lost this match in the opening ten minutes, ten bad minutes where we let two goals in, Eeal coach Zinedine zidane told Spanish TV.

Im not worried, Im angry more than anything, because we only have ourselves to blame.

Read | Real Madrid set Spanish record with last-gasp draw against Sevilla

Italian striker Zaza had broken down in tears after scoring his first goal since May at the weekend, but showed his confidence is suddenly sky high with a brilliant volleyed finish to open the scoring on five minutes.

Orellana then finished off a flowing counter-attack on nine, but Cristiano Ronaldo halved Madrids arrears with a towering header from Marcelos cross a minute before half-time.

Madrid boss Zidane introduced Gareth Bale off the bench on just his second appearance after a three-month injury layoff for the final half hour.

And the Welshman nearly rescued a point when his header from point-blank range was blocked by Enzo Perez a minute from time.

Madrids Brazilian wing-back Marcelo agreed with his coach that they had thrown the game away early.

Were still top but we really have to do something to change things, learn from our mistakes, he said.

We got off poorly and its our own fault, he said.

Madrid will take on Villarreal away on Sunday in their next La Liga game.

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Real Madrid CF battle back to win at Villarreal CF and stay on top of La Liga – Hindustan Times

Posted: at 11:22 pm

Cristiano Ronaldo and Gareth Bale scored as Real Madrid C.F. came from two goals down to beat Villareall C.F. in La Liga. Zinedine Zidane-coached Real Madrid are on top of La Liga

Cristiano Ronaldo and Gareth Bale both scored as Real Madrid staged a remarkable late comeback from two goals down to win 3-2 at Villarreal and stay top of La Liga on Sunday.

Substitute Alvaro Morata got the winner in the 83rd minute to complete a 19-minute turnaround that keeps Zinedine Zidanes side on course for their first La Liga triumph since 2012.

Real are top on 55 points, one ahead of Barcelona who beat Atletico Madrid 2-1, and three clear of Sevilla, while Zidanes side have a game in hand on both of their title rivals.

Read | Real Madrid set Spanish record with last-gasp draw against Sevilla

Villarreals Manu Trigueros lashed home from inside the area to put the hosts ahead five minutes after the break and Cedric Bakambu doubled the lead in the 57th with a fine finish past Keylor Navas, though he was fortunate not to be ruled offside.

Real looked destined for a second loss in a week on the east coast after Wednesdays 2-1 reverse at Valencia but Bale, making his first start since November, headed a goal back in the 64th before Ronaldo levelled with a penalty 10 minutes later.

Read | Shah Rukh Khan presented with Real Madrid C.F. jersey

Morata then headed Marcelos cross under Villarreals substitute goalkeeper Andres Fernandez, who had replaced first choice Sergio Asenjo when he sustained a muscle injury after making a stunning save to deny Karim Benzema.

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Real Madrid CF battle back to win at Villarreal CF and stay on top of La Liga – Hindustan Times

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Limerick CF parents: ‘Our kid’s lives are priceless’ – Limerick Leader

Posted: February 25, 2017 at 3:26 pm

STOP putting prices on our childrens lives, because to us they are priceless.

Thats the message from Katie Sheahan, whose youngest son Michael, aged three, suffers from cystic fibrosis (CF).

Parents of children who have the genetic condition, which mainly affects the lungs, are calling on Health Minister Simon Harris to make the potentially life-saving drugs Orkambi and Kaleydeco openly available.

They argue it will give their young ones a real childhood and better long-term prospects.

On Friday night last, around 90 parents whose children suffer from the condition gathered at Limerick City Hall for a vigil in memory of those who have died from the condition. But the underlying message is: they want action from the government.

Around 560,000 kids in Ireland could benefit from Orkambi or Kaleydeco, and Kate said: It will stop kids getting six weeks sickness from school, plus viruses and everyday bugs. Its a really important drug. We know its not a cure: but it gives hope to the CF community because at the moment, were living in fear of what the future holds for our children.

Orkambi is estimated to cost around 159,000 per patient per year, with pressure mounting on Mr Harristo get the drug approved for patients.

Limerick TD Willie ODea, who attended the protest, raised the matter in Dail Eireann this week.

He said: I think we all owe it to fight for these people who are literally fighting for their lives. You cannot really imagine what people who suffer from CF are going through. They struggle to breathe. Its too hard to even contemplate.

Kate, who co-organised the vigil, which was held with the support of the charity Tipperary Limerick and Clare for Cystic Fibrosis (TLC4CF), added: Stop making us wait. The CF community are living in fear. No parent should have to live like this. We are standing here tonight for all the CF mothers and fathers who cannot be here because they are caring for their loved ones in hospitals.

Joy ODonoghue, whose eight-year-old son Jason has CF, added: I dont want to have to bury my child. I dont want to have to see other people burying their children. Its not fair, its not right. Our kids lives are priceless.

At the vigil, a minutes silence was observedfor children who have lost their lives to CF.

A number of other local politicians joined Mr ODea at the vigil: former Education Minister Jan OSullivan, plus Sinn Fein councillors John Costelloe and Malachy McCreesh.

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Limerick CF parents: ‘Our kid’s lives are priceless’ – Limerick Leader

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Pawtucket man arrested for narcotics in CF – WPRI 12 Eyewitness News

Posted: February 24, 2017 at 6:32 pm

CENTRAL FALLS, R.I. (WPRI) The odor of freshly burnt marijuana was strong Thursday, when members of the Central Falls Police Department ended up arresting a driver for narcotics on Cross Street.

Officers pulled over Daniel Gilbert, 23, of Pawtucket for alleged traffic violations. Gilbert advised officers he had recently been smoking marijuana and had some left in his vehicle, according to Lt. Christopher Reed. Due to the odor, officers requested a drug-sniffing K-9 officer to search the vehicle.

The dog ended up finding a green leafy substance in individually wrapped small plastic bags on the center console. Furthermore, in the consoles ashtray, the dog led officers to a sizeable amount of white powder determined to be cocaine.

Gilbert was charged with felony drug possession, held overnight at Central Falls Police headquarters, and faced a judge Friday morning at 6th District Court in Providence. He was granted $5,000 bail with surety on Thursdays charge, but ended up being held without bail for violating probation.

According to the Rhode Island Judiciarys website, he will be due back in court May 19.

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Pawtucket man arrested for narcotics in CF – WPRI 12 Eyewitness News

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Nivalis Therapeutics (NVLS) Says Cavosonstat Phase 2 Clinical … – StreetInsider.com

Posted: at 6:32 pm

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Nivalis Therapeutics, Inc. (NASDAQ: NVLS), a pharmaceutical company historically focused on developing innovative solutions for people with cystic fibrosis (CF), today announced topline results from the Company’s Phase 2 trial evaluating the efficacy and safety of cavosonstat at a dose of 400 mg in adult patients with CF who had one copy of the F508del-CFTR mutation and a second gating mutation, and were being treated with Kalydeco (ivacaftor). There were no dose limiting toxicities and cavosonstat was well tolerated in the trial. Cavosonstat, when added to Kalydeco therapy, did not demonstrate benefit in absolute change in percent predicted FEV1, the trials primary endpoint, or in sweat chloride reduction at 8 weeks.

Summary of Key DataThe data announced today are from a Phase 2, double-blind, randomized, placebo controlled, trial that evaluated the efficacy and safety of one dose of cavosonstat administered twice daily (BID) in adult patients with CF who were heterozygous for the F508del-CFTR mutation and a gating mutation, being treated with Kalydeco. The 12-week trial included a total of 19 adults who received treatment with cavosonstat (400 mg) added to Kalydeco (n=15) or with placebo added to Kalydeco (n=4). The trial included a 4-week withdrawal and follow-up period once patients had completed 8 weeks of dosing.

The primary endpoint of the trial was change in absolute percent predicted FEV1 from baseline to week 8. These primary and key secondary endpoints are shown in the table below.

Primary and Key Secondary Endpoint at Week 8

The increase in body mass index (BMI) reflecting a gain in weight in this study was similar to increases in BMI observed in two prior studies of cavosonstat in CF patients homozygous for F508del-CFTR. In one study, cavosonstat was administered over 4 weeks to CF patients who were not being treated with OrkambiTM and in the other study cavosonstat was administered over 12 weeks to patients who were being treated with Orkambi. End of treatment BMI data from these studies are summarized in the table below. These data suggest that GSNOR inhibition may have improved the nutritional status of patients with CF in these studies.

We are sincerely grateful to those who participated in this trial, including the patients, their families, the trial investigators and our employees, said Steven Shoemaker, M.D., Medical Director at Nivalis. We hope that the data from this trial will help inform the overall body of CF research, and help others in the design of future CF trials.

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Nivalis Therapeutics (NVLS) Says Cavosonstat Phase 2 Clinical … – StreetInsider.com

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Galapagos doses first healthy volunteer with CF combo GLPG2222 and GLPG2451 – P&T Community

Posted: at 6:32 pm

Galapagos doses first healthy volunteer with CF combo GLPG2222 and GLPG2451
P&T Community
Triple combinations of CF compounds in the portfolio have consistently shown restoration of healthy activity levels in in vitro assays with human bronchial epithelial (HBE) cells of patients with the F508del mutation. These combinations result in an

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Galapagos doses first healthy volunteer with CF combo GLPG2222 and GLPG2451 – P&T Community

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CF Industries Holdings, Inc. to Participate in Upcoming Investor Conference – Yahoo Finance

Posted: February 23, 2017 at 1:21 pm

DEERFIELD, Ill.–(BUSINESS WIRE)–

CF Industries Holdings, Inc. (CF) today announced that the company will present at 8:30 a.m. ET on Thursday, March 2, 2017, at the Bank of America Merrill Lynch Global Agriculture and Chemicals Conference 2017.

Investors who wish to access the live conference webcast should visit the Investor Relations section of the companys website at http://www.cfindustries.com. A replay of the webcast will be available on the CF Industries Holdings, Inc. website until May 30, 2017.

About CF Industries Holdings, Inc.

CF Industries Holdings, Inc., headquartered in Deerfield, Illinois, through its subsidiaries is a global leader in the manufacturing and distribution of nitrogen products, serving both agricultural and industrial customers. CF Industries operates world-class nitrogen manufacturing complexes in Canada, the United Kingdom and the United States, and distributes plant nutrients through a system of terminals, warehouses, and associated transportation equipment located primarily in the Midwestern United States. The company also owns a 50 percent interest in an ammonia facility in The Republic of Trinidad and Tobago. CF Industries routinely posts investor announcements and additional information on the companys website atwww.cfindustries.comand encourages those interested in the company to check there frequently.

View source version on businesswire.com: http://www.businesswire.com/news/home/20170222006638/en/

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CF Industries Holdings, Inc. to Participate in Upcoming Investor Conference – Yahoo Finance

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Just the Facts on CF Industries Holdings, Inc. (CF) – StockNewsJournal

Posted: at 1:21 pm


StockNewsJournal
Just the Facts on CF Industries Holdings, Inc. (CF)
StockNewsJournal
CF Industries Holdings, Inc. (CF) is an interesting player in the Basic Materials space, with a focus on Agricultural Chemicals. The stock has been active on the tape, currently trading at $33.22, down from yesterday's close by -2.09%. Given the stock
EPS Projection Of CF Industries Holdings, Inc. (NYSE:CF) At $0.39Markets Daily
The Tahithromos LLC Acquires 93929 Shares of CF Industries Holdings, Inc. (CF)DailyQuint
CF Industries Holdings Inc. – Receive News & Ratings DailyBBNS
Post Analyst
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Bloomer Wins Two Games, Bit By CF McDonell Macks – Bloomer … – Bloomer Advance (subscription)

Posted: at 1:21 pm

The Bloomer Blackhawks boys basketball team beat Altoona and Barron last week, but lost to Chippewa Falls McDonell.

At Altoona Monday, Feb. 13, Bloomer outscored the Railroaders 10-4 in the final 2:17 of the first half for a 31-23 halftime lead. Altoona threatened to catch the Hawks, trailing by only two points, but Bloomer responded with a 15-0 run to go up 52-35 with 11:13 to play. The Railroaders could only cut Bloomers lead down to nine points in the remaining time in the 68-58 win.

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Bloomer Wins Two Games, Bit By CF McDonell Macks – Bloomer … – Bloomer Advance (subscription)

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CF Foundation lands big gift – Ocala

Posted: February 22, 2017 at 4:18 am

103-acre farm, valued at $2.9M plus, will help students in Equine Studies and Agribusiness programs

The College of Central Florida Foundation announced Tuesday that it has received the largest gift in its 58-year history: a 103-acre farm on County Road 475 that is valued at more than $2.9 million.

The farm will soon provide hands-on learning opportunities for students in the colleges Equine Studies and Agribusiness programs, CF said in a news release.

Though he is not named in the release, the donor is Richard E. Sherman of Ocala. He transferred the deed to the foundation on Dec. 28. One day before that the Diamondback Cattle Company, of which Sherman is the sole managing member and administrator, transferred the land to Sherman, according to land records on file with the court clerks office.

The news release identified the donor only as a longtime Marion County supporter of education and agriculture.

The farm address is 4020 SE Third Ave., Ocala. Its better known as the farm on CR 475 just north of Grace Episcopal School.

The CF Foundation was created in 1959 as the Central Florida Junior College Endowment Corp. The name has changed through the years but the mission has remained consistent: “to solicit and secure restricted and unrestricted resources to support the college in providing educational services to Citrus, Levy and Marion counties,” the foundation wrote in an email.

Until now, the foundation’s largest gift was $2.5 million from the estate of Jack Wilkinson. The money was designated for CF’s new Levy campus, which is under construction and scheduled to open in August, the foundation said.

The foundation raised $1.16 million during 2015, the latest year for which full statistics are available. That does not include the farm, which will be counted in the 2016 tally.

“The foundation has over 400 scholarships, with 363 of them endowed, to aid our students in their education journey. In 2016 we added 14 new scholarships and one endowed chair,” foundation Executive Director Chris Knife wrote in an email. (The foundation also helps find equipment and capital resources to enhance existing CF programs.)

The Equine Studies program has approximately 100 students and there are 50 in Agribusiness. Both are Associate in Science degree programs, though “the Agribusiness program also has a specialization in the Bachelor of Applied Science degree,” the foundation said.

“This year the college celebrates 60 years of providing education and workforce training in our community, and I cannot think of a better way to celebrate our past accomplishments than to look to the future,” CF President Jim Henningsen said in the news release.

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CF Foundation lands big gift – Ocala

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