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Tag Archives: health
Posted: September 18, 2016 at 8:09 am
Home Topics AZ Psoriasis
Author:Hon A/Prof Amanda Oakley, Hamilton, New Zealand. Revised and updated, August 2014.
Psoriasis is a chronic inflammatory skin condition characterised by clearly defined, red and scaly plaques (thickened skin). It is classified into several subtypes.
Psoriasis affects 24% of males and females. It can start at any age including childhood, with peaks of onset at 1525 years and 5060 years. It tends to persist lifelong, fluctuating in extent and severity. It is particularly common in Caucasians, but may affect people of any race. About one third of patients with psoriasis have family members with psoriasis.
Psoriasis is multifactorial. It is classified as an immune-mediated inflammatory disease (IMID).
Genetic factors are important. An individual’s genetic profile influences their type of psoriasis and its response to treatment.
Genome-wide association studies report that HLA-Cw6 is associated with early onset psoriasis and guttate psoriasis. This major histocompatibility complex is not associated with arthritis, nail dystrophy or late onset psoriasis.
Theories about the causes of psoriasis need to explain why the skin is red, inflamed and thickened. It is clear that immune factors and inflammatory cytokines (messenger proteins) such is IL1 and TNF are responsible for the clinical features of psoriasis. Current theories are exploring the TH17 pathway and release of the cytokine IL17A.
Psoriasis usually presents with symmetrically distributed, red, scaly plaques with well-defined edges. The scale is typically silvery white, except in skin folds where the plaques often appear shiny and they may have a moist peeling surface. The most common sites are scalp, elbows and knees, but any part of the skin can be involved. The plaques are usually very persistent without treatment.
Itch is mostly mild but may be severe in some patients, leading to scratching and lichenification (thickened leathery skin with increased skin markings). Painful skin cracks or fissures may occur.
When psoriatic plaques clear up, they may leave brown or pale marks that can be expected to fade over several months.
Certain features of psoriasis can be categorised to help determine appropriate investigations and treatment pathways. Overlap may occur.
Generalised pustulosis and localised palmoplantar pustulosis are no longer classified within the psoriasis spectrum.
Patients with psoriasis are more likely than other people to have other health conditions listed here.
Psoriasis is diagnosed by its clinical features. If necessary, diagnosis is supported by typical skin biopsy findings.
Medical assessment entails a careful history, examination, questioning about effect of psoriasis on daily life, and evaluation of comorbid factors.
Validated tools used to evaluate psoriasis include:
The severity of psoriasis is classified as mild in 60% of patients, moderate in 30% and severe in 10%.
Evaluation of comorbidities may include:
Patients with psoriasis should ensure they are well informed about their skin condition and its treatment. There are benefits from not smoking, avoiding excessive alcohol and maintaining optimal weight.
Mild psoriasis is generally treated with topical agents alone. Which treatment is selected may depend on body site, extent and severity of the psoriasis.
Most psoriasis centres offer phototherapy with ultraviolet (UV) radiation, often in combination with topical or systemic agents. Types of phototherapy include
Moderate to severe psoriasis warrants treatment with a systemic agent and/or phototherapy. The most common treatments are:
Other medicines occasionally used for psoriasis include:
Systemic corticosteroids are best avoided due to risk of severe withdrawal flare of psoriasis and adverse effects.
Biologics or targeted therapies are reserved for conventional treatment-resistant severe psoriasis, mainly because of expense, as side effects compare favourably with other systemic agents. These include:
The rest is here:
Psoriasis | DermNet New Zealand
Posted: at 8:09 am
What Is Psoriasis?
Psoriasis is a genetically programmed inflammatory disease that primarily affects the skin in about 3% of individuals in the United States. Psoriasis is characterized by skin cells that multiply up to 10 times faster than normal. When these cells reach the surface and die, raised, red plaques covered with white scales form. Psoriasis begins as a small scaling papule. When multiple papules coalesce, they form scaling plaques. These plaques tend to occur in the scalp, elbows, and knees.
Although psoriatic plaques can be limited to only a few small areas, the condition can involve widespread areas of skin anywhere on the body. Psoriasis symptoms vary depending on the type of psoriasis you have. Common psoriasis symptoms can include the following:
Plaque psoriasis is the most common type of psoriasis and it gets its name from the plaques that build up on the skin. There tend to be well-defined patches of red raised skin that can appear on any area of the skin, but the knees, elbows, scalp, trunk, and nails are the most common locations. There is also a flaky, white build up on top of the plaques, called scales. Possible plaque psoriasis symptoms include skin pain, itching, and cracking.
There are plenty of over-the-counter products that are effective in the treatment of plaque psoriasis. 1% hydrocortisone cream is a topical steroid that can suppress mild disease and preparations containing tar are effective in treating plaque psoriasis.
Scalp psoriasis is a common skin disorder that makes raised, reddish, often scaly patches. Scalp psoriasis can affect your whole scalp, or just pop up as one patch. This type of psoriasis can even spread to the forehead, the back of the neck, or behind the ears. Scalp psoriasis symptoms may include only slight, fine scaling. Moderate to severe scalp psoriasis symptoms may include dandruff-like flaking, dry scalp, and hair loss. Scalp psoriasis does not directly cause hair loss, but stress and excess scratching or picking of the scalp may result in hair loss.
Scalp psoriasis can be treated with medicated shampoos, creams, gels, oils, ointments, and soaps. Salicylic acid and coal tar are two medications in over-the-counter products that help treat scalp psoriasis. Steroid injections and phototherapy may help treat mild scalp psoriasis. Biologics are the latest class of medications that can also help treat severe scalp psoriasis.
Guttate psoriasis looks like small, pink dots or drops on the skin. The word guttate is from the Latin word gutta, meaning drop. There tends to be fine scales with guttate psoriasis that is finer than the scales in plaque psoriasis. Guttate psoriasis is typically triggered by streptococcal (strep throat) and the outbreak will usually occur two to three weeks after having strep throat.
Guttate psoriasis tends to go away after a few weeks without treatment. Moisturizers can be used to soften the skin. If there is a history of psoriasis, a doctor may take a throat culture to determine if strep throat is present. If the throat culture shows that streptococcal is present, a doctor may prescribe antibiotics.
Many patients with psoriasis have abnormal nails. Psoriatic nails often have a horizontal white or yellow margin at the tip of the nail called distal onycholysis because the nail is lifted away from the skin. There can often be small pits in the nail plate, and the nail is often yellow and crumbly.
The same treatment for skin psoriasis is beneficial for nail psoriasis. However, since nails grow slow, it may take a while for improvements to be evident. Nail psoriasis can be treated with phototherapy, systemic therapy (medications that spread throughout the body), and steroids (cream or injection). If medications do not improve the condition of nail psoriasis, a doctor may surgically remove the nail.
Psoriasis can be associated with a destructive arthritis called psoriatic arthritis. Damage can be serious enough to permanently damage the affected joints. Prevention of joint damage in such cases is very important.
Psoriatic arthritis is a chronic disease characterized by a form of inflammation of the skin and joints. About 15%-25% of patients with psoriasis also develop an inflammation of their joints. Psoriatic arthritis is a systemic rheumatic disease that can not only cause inflammation of the skin, but in the eyes, heart, kidneys, and lungs as well. Currently, the cause of psoriatic arthritis is unknown, but a combination of genetic, immune, and environmental facts is likely involved.
Typically, a patient will have psoriasis months or years before they develop psoriatic arthritis. Psoriatic arthritis usually involves the knees, ankles, and joints in the feet. There may also be a loss of range of motion of the involved joints as well as joint stiffness. Psoriatic arthritis can also cause inflammation of the spine and the sacrum, which causes pain and stiffness in the low back, buttocks, neck, and upper back.
Treatment for psoriatic arthritis generally involves anti-inflammatory medications and exercise. It is important to stretch or take a hot shower before exercise in order to relax the muscles. Ice application after exercise can help minimize soreness and inflammation. Nonsteroidal anti-inflammatory drugs may also reduce joint inflammation, pain, and stiffness.
It is now clear that there is a genetic basis for psoriasis. This hereditary predisposition is necessary before the disease can be triggered by environmental factors. White blood cells called T-cells mediate the development of the psoriatic plaques that are present in the skin. When someone has psoriasis, their body is unable to offer protection from invaders. Instead, inflammation is promoted and skin cells are on overdrive. When cell growth is increased, old skin cells pile up instead of flaking off, causing psoriasis to occur. Currently, most experts conclude that environmental, genetic and immunologic factors interact to cause the disease.
If you have the genetic basis of psoriasis, a trigger can cause psoriasis to flare up. The following are triggers that may set off ones psoriasis:
No, psoriasis is not contagious. People used to believe that psoriasis was the same as leprosy, but that is not the case. You cannot get psoriasis by touching, kissing, or having sex with someone who has psoriasis. People get psoriasis because of their genes, not their hygiene, diet, lifestyle, or any other habits.
Psoriasis is often diagnosed or at least suspected on the basis of its appearance and distribution. However, psoriasis may resemble eczema or other skin diseases and further tests may be required. It may be necessary to remove a small piece of skin (a biopsy) and have it examined by a pathologist to confirm the diagnosis. If there are joint symptoms, X-rays and other laboratory tests may be in order. Psoriasis cannot be cured, but like many other medical conditions, it is controllable with treatment. Your doctor may have you seen by a consultant such as a dermatologist, rheumatologist or immunologist to help diagnose and treat your form of psoriasis.
Since psoriasis mainly affects the skin, topical treatments are very useful because they are relatively safe, fairly effective, and can be applied directly to the affected skin. They take the form of lotions, foams, creams, ointments, gels, and shampoos. They include topical steroids, tar preparations, and calcium- modulating drugs. The precise drug used and the form in which it is delivered depends on the areas involved. In widespread disease in patients with more than 10% of the body surface involved, it may not be practical to use topical medication alone.
For more extensive psoriasis, a useful option is ultraviolet (UV) light exposure. UV light can treat large areas of skin with few side effects, if performed in the physicians office. It should be kept in mind that all UV light causes mutational events, which can lead to skin cancer. At this time, the most popular type of UV light for psoriasis is called narrow-band UVB. Only a small portion of the UV light spectrum is used, which seems to be particularly beneficial for psoriasis and may be less carcinogenic. This UVB is quite different from the UVA, the wavelength available in tanning salons, which is not effective in psoriasis. Phototherapy can be used alone or with medications when treating psoriasis.
Excimer lasers or pulsed dye lasers are used in laser therapy. A pulsed dye laser will create a concentrated beam of yellow light. When this light hits the skin, it converts to heat. The heat then destroys the extra blood vessels in the skin that contribute to psoriasis. Excimer lasers will deliver ultraviolet light to localized areas of the skin that help treat psoriasis. These lasers produce UV light in wavelengths similar to narrow-band UVB. Laser therapy uses intense doses of laser light to help control areas of mild to moderate psoriasis without damaging surrounding healthy skin. These can be quite effective for small plaques of psoriasis, but since only small areas of skin can be treated at once, they are not practical for extensive disease.
There are a variety of drugs administered systemically that are useful in controlling psoriasis. As a generalization, most oral medications act by targeting portions of the immune system. The only exception currently is a drug called acitretin (Soriatane), which is structurally similar to vitamin A. Since the immune system is necessary in order to survive, systemic treatments do have a downside. Drugs like methotrexate and cyclosporine are administered orally and can affect the liver, kidney, and bone marrow. A new oral medication recently approved for treatment of psoriasis is called Otezla (apremilast). Otezla selectively targets molecules inside immune cells and adjusts (reduces) the processes of inflammation within the cell, which in turn helps treat psoriasis. This drug appears to be considerably safer that most of its predecessors but is also quite expensive.
A new class of drugs has recently been developed called biologics; they’re called biologics because living cells synthesize them. Since these drugs are proteins, they cannot be administered orally and must be given by injection through the skin or by an intravenous infusion. This treatment is recommended in patients with moderate to severe psoriasis. These drugs target the immune response that leads to the rapid skin cell growth of psoriasis. This seems to have increased their safety profile as well as their effectiveness when compared to older drugs. On the other hand, they are quite expensive costing up to $30,000 a year.
There are many home remedies that can be used in the treatment of psoriasis. It is very important to keep the skin moist to avoid dryness. Petroleum jelly, shortening, or olive oil can be used as a moisturizer. Take fewer showers and baths to avoid stripping the skin of its natural oils. Adding salts, oil, or finely ground oatmeal to the bath can soothe the skin. Heliotherapy (medicinal sunbathing) can be effective in controlling psoriasis. There is also evidence that increased body mass is associated with psoriasis and that heavier individuals are more difficult to treat.
At the edge of Israel’s Dead Sea, there are a group of resorts that cater to psoriasis patients by offering a combination of graded solar exposure and the application of crude coal tar along with a spa-like experience. The Dead Sea is the lowest point on earth, more than 400 meters below sea level. Once the suns rays pass through the haze, the harmful ultraviolet rays are filtered out and the remaining rays are highly effective in treating psoriasis. For those with the time and the money, this is a reasonable alternative to standard medical treatment.
Although there is no doubt that psoriasis is a potent inducer of stress, the evidence that stress causes psoriasis is sparse. However, stress can make psoriasis worse, and psoriasis can make one stressed. Dealing with stress with or without psoriasis is a challenge for most people living in the 21st century. The following are tips to reduce stress:
Not only are the physical effects of psoriasis frustrating, but the emotional effects of psoriasis can be much worse. Psoriasis may cause your relationships to change and people may treat you differently. Unfortunately, this may lead to stress, which then leads to worsening psoriasis. A doctor may prescribe antidepressant medications if psoriasis is diminishing your quality of life. Support groups can also help you cope with psoriasis by talking to other people who are suffering from the same disease.
Fall and winter may bring shorter days, colder temperatures, and dry air. These can all lead to worsening psoriasis symptoms. The suns ultraviolet light hinders the rapid growth of skin cells that is characteristic of psoriasis. Therefore, spending less time in the sun may cause psoriasis symptoms to flare. The dry weather may remove moisture in your skin so it is important to use moisturizer and/or a humidifier at home.
There are many different remedies that may ease psoriasis symptoms. The following is a partial list of alternative medicine to help treat psoriasis:
Consult your doctor before trying new medications.
There is plenty of evidence that extensive psoriasis can have a very significant negative effect on a patients self-image and emotions. This is especially true in social situations, although all aspects of life can be disturbed. Inverse psoriasis, which affects the genital skin, and scalp psoriasis can be particularly troubling. Psoriasis affecting the hands may make it impossible to interact normally with others. It is important to remember that there are ways to manage and treat psoriasis flares. It may seem as if ones quality of life has diminished, but there are many organizations that offer support to psoriasis patients. The National Psoriasis Foundation is an excellent source of accurate information as well as emotional support for afflicted patients.
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Slideshow Pictures: Psoriasis — Symptoms, Causes and …
Posted: September 16, 2016 at 5:26 am
No one should ever work.
Work is the source of nearly all the misery in the world. Almost any evil you’d care to name comes from working or from living in a world designed for work. In order to stop suffering, we have to stop working.
That doesn’t mean we have to stop doing things. It does mean creating a new way of life based on play; in other words, a ludic conviviality, commensality, and maybe even art. There is more to play than child’s play, as worthy as that is. I call for a collective adventure in generalized joy and freely interdependent exuberance. Play isn’t passive. Doubtless we all need a lot more time for sheer sloth and slack than we ever enjoy now, regardless of income or occupation, but once recovered from employment-induced exhaustion nearly all of us want to act. Oblomovism and Stakhanovism are two sides of the same debased coin.
The ludic life is totally incompatible with existing reality. So much the worse for “reality,” the gravity hole that sucks the vitality from the little in life that still distinguishes it from mere survival. Curiously — or maybe not — all the old ideologies are conservative because they believe in work. Some of them, like Marxism and most brands of anarchism, believe in work all the more fiercely because they believe in so little else.
Liberals say we should end employment discrimination. I say we should end employment. Conservatives support right-to-work laws. Following Karl Marx’s wayward son-in-law Paul Lafargue I support the right to be lazy. Leftists favor full employment. Like the surrealists — except that I’m not kidding — I favor full unemployment. Trotskyists agitate for permanent revolution. I agitate for permanent revelry. But if all the ideologues (as they do) advocate work — and not only because they plan to make other people do theirs — they are strangely reluctant to say so. They will carry on endlessly about wages, hours, working conditions, exploitation, productivity, profitability. They’ll gladly talk about anything but work itself. These experts who offer to do our thinking for us rarely share their conclusions about work, for all its saliency in the lives of all of us. Among themselves they quibble over the details. Unions and management agree that we ought to sell the time of our lives in exchange for survival, although they haggle over the price. Marxists think we should be bossed by bureaucrats. Libertarians think we should be bossed by businessmen. Feminists don’t care which form bossing takes so long as the bosses are women. Clearly these ideology-mongers have serious differences over how to divvy up the spoils of power. Just as clearly, none of them have any objection to power as such and all of them want to keep us working.
You may be wondering if I’m joking or serious. I’m joking and serious. To be ludic is not to be ludicrous. Play doesn’t have to be frivolous, although frivolity isn’t triviality: very often we ought to take frivolity seriously. I’d like life to be a game — but a game with high stakes. I want to play for keeps.
The alternative to work isn’t just idleness. To be ludic is not to be quaaludic. As much as I treasure the pleasure of torpor, it’s never more rewarding than when it punctuates other pleasures and pastimes. Nor am I promoting the managed time-disciplined safety-valve called “leisure”; far from it. Leisure is nonwork for the sake of work. Leisure is the time spent recovering from work and in the frenzied but hopeless attempt to forget about work. Many people return from vacation so beat that they look forward to returning to work so they can rest up. The main difference between work and leisure is that work at least you get paid for your alienation and enervation.
I am not playing definitional games with anybody. When I say I want to abolish work, I mean just what I say, but I want to say what I mean by defining my terms in non-idiosyncratic ways. My minimum definition of work is forced labor, that is, compulsory production. Both elements are essential. Work is production enforced by economic or political means, by the carrot or the stick. (The carrot is just the stick by other means.) But not all creation is work. Work is never done for its own sake, it’s done on account of some product or output that the worker (or, more often, somebody else) gets out of it. This is what work necessarily is. To define it is to despise it. But work is usually even worse than its definition decrees. The dynamic of domination intrinsic to work tends over time toward elaboration. In advanced work-riddled societies, including all industrial societies whether capitalist of “Communist,” work invariably acquires other attributes which accentuate its obnoxiousness.
Usually — and this is even more true in “Communist” than capitalist countries, where the state is almost the only employer and everyone is an employee — work is employment, i. e., wage-labor, which means selling yourself on the installment plan. Thus 95% of Americans who work, work for somebody (or something) else. In the USSR or Cuba or Yugoslavia or any other alternative model which might be adduced, the corresponding figure approaches 100%. Only the embattled Third World peasant bastions — Mexico, India, Brazil, Turkey — temporarily shelter significant concentrations of agriculturists who perpetuate the traditional arrangement of most laborers in the last several millenia, the payment of taxes (= ransom) to the state or rent to parasitic landlords in return for being otherwise left alone. Even this raw deal is beginning to look good. All industrial (and office) workers are employees and under the sort of surveillance which ensures servility.
But modern work has worse implications. People don’t just work, they have “jobs.” One person does one productive task all the time on an or-else basis. Even if the task has a quantum of intrinsic interest (as increasingly many jobs don’t) the monotony of its obligatory exclusivity drains its ludic potential. A “job” that might engage the energies of some people, for a reasonably limited time, for the fun of it, is just a burden on those who have to do it for forty hours a week with no say in how it should be done, for the profit of owners who contribute nothing to the project, and with no opportunity for sharing tasks or spreading the work among those who actually have to do it. This is the real world of work: a world of bureaucratic blundering, of sexual harassment and discrimination, of bonehead bosses exploiting and scapegoating their subordinates who — by any rational-technical criteria — should be calling the shots. But capitalism in the real world subordinates the rational maximization of productivity and profit to the exigencies of organizational control.
The degradation which most workers experience on the job is the sum of assorted indignities which can be denominated as “discipline.” Foucault has complexified this phenomenon but it is simple enough. Discipline consists of the totality of totalitarian controls at the workplace — surveillance, rotework, imposed work tempos, production quotas, punching -in and -out, etc. Discipline is what the factory and the office and the store share with the prison and the school and the mental hospital. It is something historically original and horrible. It was beyond the capacities of such demonic dictators of yore as Nero and Genghis Khan and Ivan the Terrible. For all their bad intentions they just didn’t have the machinery to control their subjects as thoroughly as modern despots do. Discipline is the distinctively diabolical modern mode of control, it is an innovative intrusion which must be interdicted at the earliest opportunity.
Such is “work.” Play is just the opposite. Play is always voluntary. What might otherwise be play is work if it’s forced. This is axiomatic. Bernie de Koven has defined play as the “suspension of consequences.” This is unacceptable if it implies that play is inconsequential. The point is not that play is without consequences. This is to demean play. The point is that the consequences, if any, are gratuitous. Playing and giving are closely related, they are the behavioral and transactional facets of the same impulse, the play-instinct. They share an aristocratic disdain for results. The player gets something out of playing; that’s why he plays. But the core reward is the experience of the activity itself (whatever it is). Some otherwise attentive students of play, like Johan Huizinga (Homo Ludens), define it as game-playing or following rules. I respect Huizinga’s erudition but emphatically reject his constraints. There are many good games (chess, baseball, Monopoly, bridge) which are rule-governed but there is much more to play than game-playing. Conversation, sex, dancing, travel — these practices aren’t rule-governed but they are surely play if anything is. And rules can be played with at least as readily as anything else.
Work makes a mockery of freedom. The official line is that we all have rights and live in a democracy. Other unfortunates who aren’t free like we are have to live in police states. These victims obey orders or-else, no matter how arbitrary. The authorities keep them under regular surveillance. State bureaucrats control even the smaller details of everyday life. The officials who push them around are answerable only to higher-ups, public or private. Either way, dissent and disobedience are punished. Informers report regularly to the authorities. All this is supposed to be a very bad thing.
And so it is, although it is nothing but a description of the modern workplace. The liberals and conservatives and libertarians who lament totalitarianism are phonies and hypocrites. There is more freedom in any moderately deStalinized dictatorship than there is in the ordinary American workplace. You find the same sort of hierarchy and discipline in an office or factory as you do in a prison or monastery. In fact, as Foucault and others have shown, prisons and factories came in at about the same time, and their operators consciously borrowed from each other’s control techniques. A worker is a part time slave. The boss says when to show up, when to leave, and what to do in the meantime. He tells you how much work to do and how fast. He is free to carry his control to humiliating extremes, regulating, if he feels like it, the clothes you wear or how often you go to the bathroom. With a few exceptions he can fire you for any reason, or no reason. He has you spied on by snitches and supervisors, he amasses a dossier on every employee. Talking back is called “insubordination,” just as if a worker is a naughty child, and it not only gets you fired, it disqualifies you for unemployment compensation. Without necessarily endorsing it for them either, it is noteworthy that children at home and in school receive much the same treatment, justified in their case by their supposed immaturity. What does this say about their parents and teachers who work?
The demeaning system of domination I’ve described rules over half the waking hours of a majority of women and the vast majority of men for decades, for most of their lifespans. For certain purposes it’s not too misleading to call our system democracy or capitalism or — better still — industrialism, but its real names are factory fascism and office oligarchy. Anybody who says these people are “free” is lying or stupid. You are what you do. If you do boring, stupid monotonous work, chances are you’ll end up boring, stupid and monotonous. Work is a much better explanation for the creeping cretinization all around us than even such significant moronizing mechanisms as television and education. People who are regimented all their lives, handed off to work from school and bracketed by the family in the beginning and the nursing home at the end, are habituated to heirarchy and psychologically enslaved. Their aptitude for autonomy is so atrophied that their fear of freedom is among their few rationally grounded phobias. Their obedience training at work carries over into the families they start, thus reproducing the system in more ways than one, and into politics, culture and everything else. Once you drain the vitality from people at work, they’ll likely submit to heirarchy and expertise in everything. They’re used to it.
We are so close to the world of work that we can’t see what it does to us. We have to rely on outside observers from other times or other cultures to appreciate the extremity and the pathology of our present position. There was a time in our own past when the “work ethic” would have been incomprehensible, and perhaps Weber was on to something when he tied its appearance to a religion, Calvinism, which if it emerged today instead of four centuries ago would immediately and appropriately be labeled a cult. Be that as it may, we have only to draw upon the wisdom of antiquity to put work in perspective. The ancients saw work for what it is, and their view prevailed, the Calvinist cranks notwithstanding, until overthrown by industrialism — but not before receiving the endorsement of its prophets.
Let’s pretend for a moment that work doesn’t turn people into stultified submissives. Let’s pretend, in defiance of any plausible psychology and the ideology of its boosters, that it has no effect on the formation of character. And let’s pretend that work isn’t as boring and tiring and humiliating as we all know it really is. Even then, work would still make a mockery of all humanistic and democratic aspirations, just because it usurps so much of our time. Socrates said that manual laborers make bad friends and bad citizens because they have no time to fulfill the responsibilities of friendship and citizenship. He was right. Because of work, no matter what we do we keep looking at our watches. The only thing “free” about so-called free time is that it doesn’t cost the boss anything. Free time is mostly devoted to getting ready for work, going to work, returning from work, and recovering from work. Free time is a euphemism for the peculiar way labor as a factor of production not only transports itself at its own expense to and from the workplace but assumes primary responsibility for its own maintenance and repair. Coal and steel don’t do that. Lathes and typewriters don’t do that. But workers do. No wonder Edward G. Robinson in one of his gangster movies exclaimed, “Work is for saps!”
Both Plato and Xenophon attribute to Socrates and obviously share with him an awareness of the destructive effects of work on the worker as a citizen and a human being. Herodotus identified contempt for work as an attribute of the classical Greeks at the zenith of their culture. To take only one Roman example, Cicero said that “whoever gives his labor for money sells himself and puts himself in the rank of slaves.” His candor is now rare, but contemporary primitive societies which we are wont to look down upon have provided spokesmen who have enlightened Western anthropologists. The Kapauku of West Irian, according to Posposil, have a conception of balance in life and accordingly work only every other day, the day of rest designed “to regain the lost power and health.” Our ancestors, even as late as the eighteenth century when they were far along the path to our present predicament, at least were aware of what we have forgotten, the underside of industrialization. Their religious devotion to “St. Monday” — thus establishing a de facto five-day week 150-200 years before its legal consecration — was the despair of the earliest factory owners. They took a long time in submitting to the tyranny of the bell, predecessor of the time clock. In fact it was necessary for a generation or two to replace adult males with women accustomed to obedience and children who could be molded to fit industrial needs. Even the exploited peasants of the ancient regime wrested substantial time back from their landlord’s work. According to Lafargue, a fourth of the French peasants’ calendar was devoted to Sundays and holidays, and Chayanov’s figures from villages in Czarist Russia — hardly a progressive society — likewise show a fourth or fifth of peasants’ days devoted to repose. Controlling for productivity, we are obviously far behind these backward societies. The exploited muzhiks would wonder why any of us are working at all. So should we.
To grasp the full enormity of our deterioration, however, consider the earliest condition of humanity, without government or property, when we wandered as hunter-gatherers. Hobbes surmised that life was then nasty, brutish and short. Others assume that life was a desperate unremitting struggle for subsistence, a war waged against a harsh Nature with death and disaster awaiting the unlucky or anyone who was unequal to the challenge of the struggle for existence. Actually, that was all a projection of fears for the collapse of government authority over communities unaccustomed to doing without it, like the England of Hobbes during the Civil War. Hobbes’ compatriots had already encountered alternative forms of society which illustrated other ways of life — in North America, particularly — but already these were too remote from their experience to be understandable. (The lower orders, closer to the condition of the Indians, understood it better and often found it attractive. Throughout the seventeenth century, English settlers defected to Indian tribes or, captured in war, refused to return. But the Indians no more defected to white settlements than Germans climb the Berlin Wall from the west.) The “survival of the fittest” version — the Thomas Huxley version — of Darwinism was a better account of economic conditions in Victorian England than it was of natural selection, as the anarchist Kropotkin showed in his book Mutual Aid, A Factor of Evolution. (Kropotkin was a scientist — a geographer — who’d had ample involuntary opportunity for fieldwork whilst exiled in Siberia: he knew what he was talking about.) Like most social and political theory, the story Hobbes and his successors told was really unacknowledged autobiography.
The anthropologist Marshall Sahlins, surveying the data on contemporary hunter-gatherers, exploded the Hobbesian myth in an article entitled “The Original Affluent Society.” They work a lot less than we do, and their work is hard to distinguish from what we regard as play. Sahlins concluded that “hunters and gatherers work less than we do; and rather than a continuous travail, the food quest is intermittent, leisure abundant, and there is a greater amount of sleep in the daytime per capita per year than in any other condition of society.” They worked an average of four hours a day, assuming they were “working” at all. Their “labor,” as it appears to us, was skilled labor which exercised their physical and intellectual capacities; unskilled labor on any large scale, as Sahlins says, is impossible except under industrialism. Thus it satisfied Friedrich Schiller’s definition of play, the only occasion on which man realizes his complete humanity by giving full “play” to both sides of his twofold nature, thinking and feeling. As he put it: “The animal works when deprivation is the mainspring of its activity, and it plays when the fullness of its strength is this mainspring, when superabundant life is its own stimulus to activity.” (A modern version — dubiously developmental — is Abraham Maslow’s counterposition of “deficiency” and “growth” motivation.) Play and freedom are, as regards production, coextensive. Even Marx, who belongs (for all his good intentions) in the productivist pantheon, observed that “the realm of freedom does not commence until the point is passed where labor under the compulsion of necessity and external utility is required.” He never could quite bring himself to identify this happy circumstance as what it is, the abolition of work — it’s rather anomalous, after all, to be pro-worker and anti-work — but we can.
The aspiration to go backwards or forwards to a life without work is evident in every serious social or cultural history of pre-industrial Europe, among them M. Dorothy George’s England In Transition and Peter Burke’s Popular Culture in Early Modern Europe. Also pertinent is Daniel Bell’s essay, “Work and its Discontents,” the first text, I believe, to refer to the “revolt against work” in so many words and, had it been understood, an important correction to the complacency ordinarily associated with the volume in which it was collected, The End of Ideology. Neither critics nor celebrants have noticed that Bell’s end-of-ideology thesis signaled not the end of social unrest but the beginning of a new, uncharted phase unconstrained and uninformed by ideology. It was Seymour Lipset (in Political Man), not Bell, who announced at the same time that “the fundamental problems of the Industrial Revolution have been solved,” only a few years before the post- or meta-industrial discontents of college students drove Lipset from UC Berkeley to the relative (and temporary) tranquility of Harvard.
As Bell notes, Adam Smith in The Wealth of Nations, for all his enthusiasm for the market and the division of labor, was more alert to (and more honest about) the seamy side of work than Ayn Rand or the Chicago economists or any of Smith’s modern epigones. As Smith observed: “The understandings of the greater part of men are necessarily formed by their ordinary employments. The man whose life is spent in performing a few simple operations… has no occasion to exert his understanding… He generally becomes as stupid and ignorant as it is possible for a human creature to become.” Here, in a few blunt words, is my critique of work. Bell, writing in 1956, the Golden Age of Eisenhower imbecility and American self-satisfaction, identified the unorganized, unorganizable malaise of the 1970’s and since, the one no political tendency is able to harness, the one identified in HEW’s report Work in America, the one which cannot be exploited and so is ignored. That problem is the revolt against work. It does not figure in any text by any laissez-faire economist — Milton Friedman, Murray Rothbard, Richard Posner — because, in their terms, as they used to say on Star Trek, “it does not compute.”
If these objections, informed by the love of liberty, fail to persuade humanists of a utilitarian or even paternalist turn, there are others which they cannot disregard. Work is hazardous to your health, to borrow a book title. In fact, work is mass murder or genocide. Directly or indirectly, work will kill most of the people who read these words. Between 14,000 and 25,000 workers are killed annually in this country on the job. Over two million are disabled. Twenty to twenty-five million are injured every year. And these figures are based on a very conservative estimation of what constitutes a work-related injury. Thus they don’t count the half million cases of occupational disease every year. I looked at one medical textbook on occupational diseases which was 1,200 pages long. Even this barely scratches the surface. The available statistics count the obvious cases like the 100,000 miners who have black lung disease, of whom 4,000 die every year, a much higher fatality rate than for AIDS, for instance, which gets so much media attention. This reflects the unvoiced assumption that AIDS afflicts perverts who could control their depravity whereas coal-mining is a sacrosanct activity beyond question. What the statistics don’t show is that tens of millions of people have heir lifespans shortened by work — which is all that homicide means, after all. Consider the doctors who work themselves to death in their 50’s. Consider all the other workaholics.
Even if you aren’t killed or crippled while actually working, you very well might be while going to work, coming from work, looking for work, or trying to forget about work. The vast majority of victims of the automobile are either doing one of these work-obligatory activities or else fall afoul of those who do them. To this augmented body-count must be added the victims of auto-industrial pollution and work-induced alcoholism and drug addiction. Both cancer and heart disease are modern afflictions normally traceable, directly, or indirectly, to work.
Work, then, institutionalizes homicide as a way of life. People think the Cambodians were crazy for exterminating themselves, but are we any different? The Pol Pot regime at least had a vision, however blurred, of an egalitarian society. We kill people in the six-figure range (at least) in order to sell Big Macs and Cadillacs to the survivors. Our forty or fifty thousand annual highway fatalities are victims, not martyrs. They died for nothing — or rather, they died for work. But work is nothing to die for.
Bad news for liberals: regulatory tinkering is useless in this life-and-death context. The federal Occupational Safety and Health Administration was designed to police the core part of the problem, workplace safety. Even before Reagan and the Supreme Court stifled it, OSHA was a farce. At previous and (by current standards) generous Carter-era funding levels, a workplace could expect a random visit from an OSHA inspector once every 46 years.
State control of the economy is no solution. Work is, if anything, more dangerous in the state-socialist countries than it is here. Thousands of Russian workers were killed or injured building the Moscow subway. Stories reverberate about covered-up Soviet nuclear disasters which make Times Beach and Three-Mile Island look like elementary-school air-raid drills. On the other hand, deregulation, currently fashionable, won’t help and will probably hurt. From a health and safety standpoint, among others, work was at its worst in the days when the economy most closely approximated laissez-faire.
Historians like Eugene Genovese have argued persuasively that — as antebellum slavery apologists insisted — factory wage-workers in the Northern American states and in Europe were worse off than Southern plantation slaves. No rearrangement of relations among bureaucrats and businessmen seems to make much difference at the point of production. Serious enforcement of even the rather vague standards enforceable in theory by OSHA would probably bring the economy to a standstill. The enforcers apparently appreciate this, since they don’t even try to crack down on most malefactors.
What I’ve said so far ought not to be controversial. Many workers are fed up with work. There are high and rising rates of absenteeism, turnover, employee theft and sabotage, wildcat strikes, and overall goldbricking on the job. There may be some movement toward a conscious and not just visceral rejection of work. And yet the prevalent feeling, universal among bosses and their agents and also widespread among workers themselves is that work itself is inevitable and necessary.
I disagree. It is now possible to abolish work and replace it, insofar as it serves useful purposes, with a multitude of new kinds of free activities. To abolish work requires going at it from two directions, quantitative and qualitative. On the one hand, on the quantitative side, we have to cut down massively on the amount of work being done. At present most work is useless or worse and we should simply get rid of it. On the other hand — and I think this is the crux of the matter and the revolutionary new departure — we have to take what useful work remains and transform it into a pleasing variety of game-like and craft-like pastimes, indistinguishable from other pleasurable pastimes, except that they happen to yield useful end-products. Surely that shouldn’t make them less enticing to do. Then all the artificial barriers of power and property could come down. Creation could become recreation. And we could all stop being afraid of each other.
I don’t suggest that most work is salvageable in this way. But then most work isn’t worth trying to save. Only a small and diminishing fraction of work serves any useful purpose independent of the defense and reproduction of the work-system and its political and legal appendages. Twenty years ago, Paul and Percival Goodman estimated that just five percent of the work then being done — presumably the figure, if accurate, is lower now — would satisfy our minimal needs for food, clothing, and shelter. Theirs was only an educated guess but the main point is quite clear: directly or indirectly, most work serves the unproductive purposes of commerce or social control. Right off the bat we can liberate tens of millions of salesmen, soldiers, managers, cops, stockbrokers, clergymen, bankers, lawyers, teachers, landlords, security guards, ad-men and everyone who works for them. There is a snowball effect since every time you idle some bigshot you liberate his flunkeys and underlings also. Thus the economy implodes.
Forty percent of the workforce are white-collar workers, most of whom have some of the most tedious and idiotic jobs ever concocted. Entire industries, insurance and banking and real estate for instance, consist of nothing but useless paper-shuffling. It is no accident that the “tertiary sector,” the service sector, is growing while the “secondary sector” (industry) stagnates and the “primary sector” (agriculture) nearly disappears. Because work is unnecessary except to those whose power it secures, workers are shifted from relatively useful to relatively useless occupations as a measure to assure public order. Anything is better than nothing. That’s why you can’t go home just because you finish early. They want your time, enough of it to make you theirs, even if they have no use for most of it. Otherwise why hasn’t the average work week gone down by more than a few minutes in the past fifty years?
Next we can take a meat-cleaver to production work itself. No more war production, nuclear power, junk food, feminine hygiene deodorant — and above all, no more auto industry to speak of. An occasional Stanley Steamer or Model-T might be all right, but the auto-eroticism on which such pestholes as Detroit and Los Angeles depend on is out of the question. Already, without even trying, we’ve virtually solved the energy crisis, the environmental crisis and assorted other insoluble social problems.
Finally, we must do away with far and away the largest occupation, the one with the longest hours, the lowest pay and some of the most tedious tasks around. I refer to housewives doing housework and child-rearing. By abolishing wage-labor and achieving full unemployment we undermine the sexual division of labor. The nuclear family as we know it is an inevitable adaptation to the division of labor imposed by modern wage-work. Like it or not, as things have been for the last century or two it is economically rational for the man to bring home the bacon, for the woman to do the shitwork to provide him with a haven in a heartless world, and for the children to be marched off to youth concentration camps called “schools,” primarily to keep them out of Mom’s hair but still under control, but incidentally to acquire the habits of obedience and punctuality so necessary for workers. If you would be rid of patriarchy, get rid of the nuclear family whose unpaid “shadow work,” as Ivan Illich says, makes possible the work-system that makes it necessary. Bound up with this no-nukes strategy is the abolition of childhood and the closing of the schools. There are more full-time students than full-time workers in this country. We need children as teachers, not students. They have a lot to contribute to the ludic revolution because they’re better at playing than grown-ups are. Adults and children are not identical but they will become equal through interdependence. Only play can bridge the generation gap.
I haven’t as yet even mentioned the possibility of cutting way down on the little work that remains by automating and cybernizing it. All the scientists and engineers and technicians freed from bothering with war research and planned obsolescence would have a good time devising means to eliminate fatigue and tedium and danger from activities like mining. Undoubtedly they’ll find other projects to amuse themselves with. Perhaps they’ll set up world-wide all-inclusive multi-media communications systems or found space colonies. Perhaps. I myself am no gadget freak. I wouldn’t care to live in a pushbutton paradise. I don’t want robot slaves to do everything; I want to do things myself. There is, I think, a place for labor-saving technology, but a modest place. The historical and pre-historical record is not encouraging. When productive technology went from hunting-gathering to agriculture and on to industry, work increased while skills and self-determination diminished. The further evolution of industrialism has accentuated what Harry Braverman called the degradation of work. Intelligent observers have always been aware of this. John Stuart Mill wrote that all the labor-saving inventions ever devised haven’t saved a moment’s labor. Karl Marx wrote that “it would be possible to write a history of the inventions, made since 1830, for the sole purpose of supplying capital with weapons against the revolts of the working class.” The enthusiastic technophiles — Saint-Simon, Comte, Lenin, B. F. Skinner — have always been unabashed authoritarians also; which is to say, technocrats. We should be more than sceptical about the promises of the computer mystics. They work like dogs; chances are, if they have their way, so will the rest of us. But if they have any particularized contributions more readily subordinated to human purposes than the run of high tech, let’s give them a hearing.
What I really want to see is work turned into play. A first step is to discard the notions of a “job” and an “occupation.” Even activities that already have some ludic content lose most of it by being reduced to jobs which certain people, and only those people are forced to do to the exclusion of all else. Is it not odd that farm workers toil painfully in the fields while their air-conditioned masters go home every weekend and putter about in their gardens? Under a system of permanent revelry, we will witness the Golden Age of the dilettante which will put the Renaissance to shame. There won’t be any more jobs, just things to do and people to do them.
The secret of turning work into play, as Charles Fourier demonstrated, is to arrange useful activities to take advantage of whatever it is that various people at various times in fact enjoy doing. To make it possible for some people to do the things they could enjoy it will be enough just to eradicate the irrationalities and distortions which afflict these activities when they are reduced to work. I, for instance, would enjoy doing some (not too much) teaching, but I don’t want coerced students and I don’t care to suck up to pathetic pedants for tenure.
Second, there are some things that people like to do from time to time, but not for too long, and certainly not all the time. You might enjoy baby-sitting for a few hours in order to share the company of kids, but not as much as their parents do. The parents meanwhile, profoundly appreciate the time to themselves that you free up for them, although they’d get fretful if parted from their progeny for too long. These differences among individuals are what make a life of free play possible. The same principle applies to many other areas of activity, especially the primal ones. Thus many people enjoy cooking when they can practice it seriously at their leisure, but not when they’re just fueling up human bodies for work.
Third — other things being equal — some things that are unsatisfying if done by yourself or in unpleasant surroundings or at the orders of an overlord are enjoyable, at least for a while, if these circumstances are changed. This is probably true, to some extent, of all work. People deploy their otherwise wasted ingenuity to make a game of the least inviting drudge-jobs as best they can. Activities that appeal to some people don’t always appeal to all others, but everyone at least potentially has a variety of interests and an interest in variety. As the saying goes, “anything once.” Fourier was the master at speculating how aberrant and perverse penchants could be put to use in post-civilized society, what he called Harmony. He thought the Emperor Nero would have turned out all right if as a child he could have indulged his taste for bloodshed by working in a slaughterhouse. Small children who notoriously relish wallowing in filth could be organized in “Little Hordes” to clean toilets and empty the garbage, with medals awarded to the outstanding. I am not arguing for these precise examples but for the underlying principle, which I think makes perfect sense as one dimension of an overall revolutionary transformation. Bear in mind that we don’t have to take today’s work just as we find it and match it up with the proper people, some of whom would have to be perverse indeed. If technology has a role in all this it is less to automate work out of existence than to open up new realms for re/creation. To some extent we may want to return to handicrafts, which William Morris considered a probable and desirable upshot of communist revolution. Art would be taken back from the snobs and collectors, abolished as a specialized department catering to an elite audience, and its qualities of beauty and creation restored to integral life from which they were stolen by work. It’s a sobering thought that the grecian urns we write odes about and showcase in museums were used in their own time to store olive oil. I doubt our everyday artifacts will fare as well in the future, if there is one. The point is that there’s no such thing as progress in the world of work; if anything it’s just the opposite. We shouldn’t hesitate to pilfer the past for what it has to offer, the ancients lose nothing yet we are enriched.
The reinvention of daily life means marching off the edge of our maps. There is, it is true, more suggestive speculation than most people suspect. Besides Fourier and Morris — and even a hint, here and there, in Marx — there are the writings of Kropotkin, the syndicalists Pataud and Pouget, anarcho-communists old (Berkman) and new (Bookchin). The Goodman brothers’ Communitas is exemplary for illustrating what forms follow from given functions (purposes), and there is something to be gleaned from the often hazy heralds of alternative/appropriate/intermediate/convivial technology, like Schumacher and especially Illich, once you disconnect their fog machines. The situationists — as represented by Vaneigem’s Revolution of Daily Life and in the Situationist International Anthology — are so ruthlessly lucid as to be exhilarating, even if they never did quite square the endorsement of the rule of the worker’s councils with the abolition of work. Better their incongruity, though than any extant version of leftism, whose devotees look to be the last champions of work, for if there were no work there would be no workers, and without workers, who would the left have to organize?
So the abolitionists would be largely on their own. No one can say what would result from unleashing the creative power stultified by work. Anything can happen. The tiresome debater’s problem of freedom vs. necessity, with its theological overtones, resolves itself practically once the production of use-values is coextensive with the consumption of delightful play-activity.
Life will become a game, or rather many games, but not — as it is now – — a zero/sum game. An optimal sexual encounter is the paradigm of productive play, The participants potentiate each other’s pleasures, nobody keeps score, and everybody wins. The more you give, the more you get. In the ludic life, the best of sex will diffuse into the better part of daily life. Generalized play leads to the libidinization of life. Sex, in turn, can become less urgent and desperate, more playful. If we play our cards right, we can all get more out of life than we put into it; but only if we play for keeps.
No one should ever work. Workers of the world… relax!
Originally posted here:
Posted: at 5:26 am
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Posted: September 8, 2016 at 6:39 am
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Posted: at 6:31 am
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Help Rejuvenate Your Body by Boosting Your Own Stem Cells
As a child, we are protected from the ravages of aging and can rapidly recover from injury or illness because of the ability of the young regenerative stem cells of children have a superior ability to repair and regenerate most damaged tissues. As we age, our stem cell populations become depleted and/or slowly lose their capacity to repair. Moreover, the micro-environment (i.e. niches) around stem cells becomes less nurturing with age, so cell turnover and repair are further reduced. This natural progression occurs so slowly that we are barely aware of it, but we start to notice the body changes in our 20s, 30s, 40s, and especially after 50 years of age. Stem Cell 100 helps adults regain their youthful regenerative potential by stabilizing stem cell function.
Stem Cell 100 works differently than other stem cell products on the market
You may have seen a number of products that are advertised as stimulating or enhancing the number of stem cells. Each person only has a limited number of stem cells so using them up faster may not be a good strategy. Stem Cell 100 is about improving the effectiveness and longevity of your stem cells as well as preserving the stem cell micro-environment. That should be the goal of any effective stem cell therapy and is what Stem Cell 100 is designed to do and what other stem cell products cannot do.
Stem Cell 100 Extends Drosophila (Fruit Fly) Lifespan
In extensive laboratory testing Stem Cell 100 greatly extended both the average and maximum lifespan of Drosophila fruit flies. The study (see Charts below) included three cages of Drosophila fruit flies that were treated with Stem Cell 100 (Cages T1 to T3) and three cages which were untreated controls (Cages C1 to C3). Each cage started with 500 fruit flies including 250 males and 250 females. The experiment showed that median lifespan more than doubled with a 123% increase. While fruit flies are not people they are more like us than you might think. Drosophila have a heart and circulatory system, and the most common cause of death is heart failure. Like humans and other mammals (e.g. mice), it is difficult to increase their lifespan significantly. These observed results outperform every lifespan enhancing treatment ever tested – including experiments using genetic modification and dietary restriction.
The longest living fruit fly receiving Stem Cell 100 lived 89 days compared to the longest living untreated control which lived 48 days. It is possible that the single longest living fruit fly lived longer for other reasons such as genetic mutation, however, there were many others that lived almost as long so it was not just an aberation. The oldest 5% of the treated fruit flies lived 77% longer than the oldest 5% of the control group. It is also important that the study showed an improved ability of the fruit flies to survive stress and illness at all ages not just during old age. Even after the first few days of the study there were already more of the Stem Cell 100 treated fruit flies alive that survived youth than the control group of untreated fruit flies. For additional information about the study please go to our Longevity page.
Stem Cell 100 is a Patent-Pending Life Code Nutraceutical. All Life Code products are nutraceutical grade and provide the best of science along with the balance of nature.
All Life Code products are nutraceutical grade and provide the best of science along with the balance of nature.
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Stem Cell 100 Plus+ is a more powerful and faster acting version of Stem Cell 100.
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Serving Size: One type O capsule
Servings Per Container: 60 Capsules
Recommended Use: Typical usage of Stem Cell 100 is two capsules per day, preferably at meal times. While both capsules can be taken at the same time, it is preferable to separate the two capsules by at least 4 hours. Since Stem Cell 100 is a potent formulation, do not take more than three capsules per day. One capsule per day may be sufficient for those below 110 pounds.
Recommended Users: Anyone from ages 22 and up could benefit from Stem Cell 100. Those in their 20s and 30s will like the boost in endurance during sports or exercise, while older users will notice better energy and general health with the potential for some weight loss.
Active Ingredients in Stem Cell 100: There are ten herbal components that make up the patent-pending combination in Stem Cell 100. The herbal components are highly extracted natural herbs that are standardized for active components that promote adult stem cells and lower inflammation:
1) Polysaccharides, flavonoids, and astragalosides extracted from Astragalus membranaceus, which has many positive effects on stem cells and the cardiovascular and immune systems.
2) Proprietary natural bilberry flavonoids and other compounds from a stabilized nutraceutical grade medicinal Vaccinium extract. Activate metabolic PPARS and helps produce healthy levels of cholesterol and silent inflammation. Also has anti-fungal and anti-viral activity.
3) Flavonoids and oligo-proanthocyanidins (OPCs) extracted from Pine Bark, which greatly reduce oxidative stress, DNA damage, and inflammation.
4) L-Theanine, which is a natural amino acid from Camellia sinesis that reduces mental stress and inflammation while improving cognition and protecting brain cells from ischemic or toxic injury.
5) Pterocarpus Marsupium, which contains two stable resveratrol analogs which promote stem cells, lower inflammation, and stabilized metabolism.
6) Polygonum Multiflorium stem stem is a popular Chinese herbal tonic that fights premature aging and promotes youthfulness. Polygonum is reported to enhance fertility by improving sperm count in men and egg vitality in women. Polygonum is also widely used in Asia to strengthen muscle and is thus used by many athletes as an essential tonic for providing strength and stamina to the body. Modern research has supported Polygonum multiflorium stem in that animal studies have proven that it can extend lifespan and improve the quality of life. Polygonum appears to protect the liver and brain against damage, perhaps by improving immune and cardiovascular health. The stem sections of Polygonum multiflorium are also calming to the nervous system and promote sounder sleep. Life Code uses a proprietary Polygonum multiflorium stem extract.
7) Schisandra Berry is used by many Chinese women to preserve their youthful beauty. For thousands of years, Schisandra has been prized as an antiaging tonic that increases stamina and mental clarity, while fighting stress and fatigue. In Chinese traditional medicine, Schisandra berry has been used for liver disorders and to enhance resistance to infection and promote skin health and better sleep. Schisandra berry is classified as an adaptogen, which can stimulate the central nervous system, increase brain efficiency, improve reflexes, and enhance endurance. Modern research indicates that Schisandra berry extracts have a protective effect on the liver and promote immunity. A double-blind human trial suggested that Schisandra berry may help patients with viral hepatitis, which is very prevalent in China. Recent work indicates that the liver is protected by the enhanced production of glutathione peroxidase, which helps detoxify the liver. Life Code uses a proprietary Schisandra berry extract.
8) Fo-Ti Root (aka He-Shou-Wu) is one of the most widely used Chinese herbal medicines to restore blood, kidney, liver, and cardiovascular health. Fo-Ti is claimed to have powerful rejuvenating effects on the brain, endocrine glands, the immune system, and sexual vigor. Legend has it that Professor Li Chung Yun took daily doses of Fo-Ti to live to be 256 and is said to have outlived 23 wives and spawned 11 generations of descendents before his death in 1933. While it is unlikely that he really lived to such an old age there is scientific support for Fo-Ti as beneficial for health and longevity. Like the Indian Keno bark, Fo-ti contains resveratrol analogs and likely acts by various mechanism, which includes liver detoxification and protection of skin from UVB radiation. Life CodeTM uses a proprietary Fo-Ti root extract.
9 ) Camellia sinensis has many bioactive polyphenols including the potent epigallocatechin-3-gallate (EGCG). A 2006 Japanese study published in the Journal of the American Medical Association reports that adults aged 40 to 79 years of age who drank an average of 5 or more cups of tea per day had a significantly lower risk of dying from all causes (23% lower for females and 12% lower for males). The study tracked more than 40,000 adults for up to 11 years and found dramatically lower rates of cardiovascular disease and strokes in those drinking 5 or more cups of tea. Many studies have found that adults drinking 3 or more cups of tea per day have significantly less cancer. Other studies have found that green tea helps protect against age-related cognitive decline, kidney disease, periodontal disease, and type 2 diabetes. Green tea also promotes visceral fat loss and higher endurance levels. Summarizing all of the thousands of studies on tea and tea polyphenols that have been published, it can be concluded that tea polyphenols preserve health and youth. This conclusion is backed up by gene studies showing that tea polyphenols decrease insulin-like growth factor-1 (IGF-1), which is a highly conserved genetic pathway that has been strongly linked to aging in yeast, worms, mice, and humans. If everyone could drink 4 to 5 cups of green tea each day, they could enjoy these important health benefits, but for most people drinking that much green tea can disturb their sleep patterns. Life Code uses a nutraceutical grade green tea extract that has 98% polyphenols and 50% ESCG that provides the polyphenol and ESCG equivalent of 4 to 5 cups of green tea with only 2% of the caffeine. Thus, most or all of the benefits of green tea are provided without concerns about disturbing sleep.
10) Drynaria Rhizome is used extensively in traditional Chinese medicine as an effective herb for healing bones, ligaments, tendons, and lower back problems. Eastern martial art practitioners have used Drynaria for thousands of years to help in recovering from sprains, bruises, and stress fractures. Drynaria has also helped in many cases of bleeding gums and tinnitus (ringing in the ears). The active components of Drynaria protect bone forming cells by enhancing calcium absorption and other mechanisms. Drynaria is also reported to act as a kidney tonic and to promote hair growth and wound healing. Life Code uses a proprietary Drynaria rhizome extract.
Active Ingredients in Stem Cell 100+ There are 11 herbal extracts in Stem Cell 100+ along with two nutraceutical grade vitamins Methyl Folate (5-MTHF) and Methyl B12 that are bioavailable vitamin supplements that are highly potent but rarely found. The highly extracted natural herbs are standardized for active components that promote adult stem cells and lower inflammation and have been tested as a synergistic herbal formulation with the proper dosage of each component:
1) Polysaccharides, flavonoids, and astragalosides extracted from Astragalus membranaceus, which has many positive effects on stem cells and the cardiovascular and immune systems. Astragalus has been used for thousands of years in Traditional Chinese Medicine (TCM) to promote cardiovascular and immune health. Astragalus is also known as a primary stimulator of Qi (Life Force). Life Code uses a high quality proprietary TCM extract that tested highest in our longevity experiments.
2) Proprietary natural bilberry flavonoids and other compounds from a stabilized nutraceutical grade medicinal Vaccinium extract. Activate metabolic PPARS and helps produce healthy levels of cholesterol and silent inflammation. Also has anti-fungal and anti-viral activity.
3) Flavonoids and oligo-proanthocyanidins (OPCs) extracted from Pine Bark, which promote the vascular system and reduce oxidative stress, DNA damage, and inflammation.
4) L-Theanine, which is a natural amino acid from Camellia sinesis that reduces mental stress and inflammation while improving cognition and protecting brain cells from ischemic or toxic injury. Life Code tested supplement with Mass Spec to verify high purity.
5) Genistein, which is an isoflavone phytoestrogen, activates telomerase, metabolic PPARs, autophagy (cell waste disposal), and smooth muscles. It also inhibits DNA methylation and the carbohydrate transporter GLUT1. Life Code tested supplement with Mass Spec to verify high purity.
6) Harataki Extract (aka Terminalia chebula) contains rejuvenating tannin flavonoids that have doubled human cell longevity in culture while maintaining telomere length. In Traditional Indian Medicine, Harataki has been used to treat skin disorders and heart disease, among many other uses.
7) Two stable resveratrol analogs from extracts of Pterocarpus Marsupium, which promote stem cells, less silent inflammation, and better metabolism. Life Code uses a highly purified proprietary source that is only available to Indian doctors. Life Code does not recommend taking resveratrol supplements or synthetic analogs, as these supplements are inherently unstable.
8) He-Shou-Wu is one of the most widely used Chinese herbal medicines to restore blood, kidney, liver, and cardiovascular health. He-Shou-Wu is claimed to have powerful rejuvenating effects on the brain, endocrine glands, the immune system, and sexual vigor. Legend has it that Professor Li Chung Yun took daily doses to live to 256 years and is said to have outlived 23 wives and spawned 11 generations of descendants before his death in 1933. While it is unlikely that he really lived to such an old age, there is scientific support for He-Shou-Wu as beneficial for health and longevity. Life Code uses a proprietary TCM He-Shou-Wu root extract.
9) Schisandra Berry is used by many Chinese women to preserve their youthful beauty. For thousands of years, Schisandra has been prized as an antiaging tonic that increases stamina and mental clarity, while fighting stress and fatigue. In TCM, Schisandra berry has been used for liver disorders and to enhance resistance to infection and promote skin health and better sleep. Schisandra berry is classified as an adaptogen, which can stimulate the central nervous system, increase brain efficiency, improve reflexes, and enhance endurance. Life Code uses a proprietary TCM extract.
10) Drynaria Rhizome is used extensively in TCM as an effective herb for healing bones, ligaments, tendons, and lower back problems. Eastern martial art practitioners have used Drynaria for thousands of years to help in recovering from sprains, bruises, and stress fractures. The active components of Drynaria protect bone forming cells by enhancing calcium absorption and other mechanisms. Drynaria is also reported to act as a kidney tonic and to promote hair growth and wound healing. Life Code uses a proprietary TCM Drynaria rhizome extract.
11) BioPerine is a proprietary brand of peperine extracted from black pepper. BioPerine has been shown to enhance bioavailability of herbal extracts. Piperine has been shown in rats to have cognitive enhancing effects and to help control silent inflammation.
Safety: The extracts in Stem Cell 100 and Stem Cell 100+ are nutraceutical grade and have been individually tested in both animals and humans without significant safety issues. Those with pre-existing conditions of diabetes or hypertension should coordinate this product with your doctor, as lower blood glucose or reduced blood pressure can result from taking the recommended dose of this product.
Warnings: may lower glucose and/or blood pressure in some individuals. The supplement is not recommended for pregnant, lactating, or hypoglycemic individuals.
1. Yu, Q., Y.S. Bai, and J. Lin, [Effect of astragalus injection combined with mesenchymal stem cells transplantation for repairing the Spinal cord injury in rats]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2010. 30(4): p. 393-7.
2. Xu, C.J., et al., [Effect of astragalus polysaccharides on the proliferation and ultrastructure of dog bone marrow stem cells induced into osteoblasts in vitro]. Hua Xi Kou Qiang Yi Xue Za Zhi, 2007. 25(5): p. 432-6.
3. Xu, C.J., et al., [Effects of astragalus polysaccharides-chitosan/polylactic acid scaffolds and bone marrow stem cells on repairing supra-alveolar periodontal defects in dogs]. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2006. 31(4): p. 512-7.
4. Zhu, X. and B. Zhu, [Effect of Astragalus membranaceus injection on megakaryocyte hematopoiesis in anemic mice]. Hua Xi Yi Ke Da Xue Xue Bao, 2001. 32(4): p. 590-2.
5. Qiu, L.H., X.J. Xie, and B.Q. Zhang, Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation. Biol Pharm Bull, 2010. 33(4): p. 641-6.
6. Araghi-Niknam, M., et al., Pine bark extract reduces platelet aggregation. Integr Med, 2000. 2(2): p. 73-77.
7. Rohdewald, P., A review of the French maritime pine bark extract (Pycnogenol), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther, 2002. 40(4): p. 158-68.
8. Koch, R., Comparative study of Venostasin and Pycnogenol in chronic venous insufficiency. Phytother Res, 2002. 16 Suppl 1: p. S1-5.
9. Rimando, A.M., et al., Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem, 2005. 53(9): p. 3403-7.
10. Manickam, M., et al., Antihyperglycemic activity of phenolics from Pterocarpus marsupium. J Nat Prod, 1997. 60(6): p. 609-10.
11. Grover, J.K., V. Vats, and S.S. Yadav, Pterocarpus marsupium extract (Vijayasar) prevented the alteration in metabolic patterns induced in the normal rat by feeding an adequate diet containing fructose as sole carbohydrate. Diabetes Obes Metab, 2005. 7(4): p. 414-20.
12. Mao, X.Q., et al., Astragalus polysaccharide reduces hepatic endoplasmic reticulum stress and restores glucose homeostasis in a diabetic KKAy mouse model. Acta Pharmacol Sin, 2007. 28(12): p. 1947-56.
13. Schafer, A. and P. Hogger, Oligomeric procyanidins of French maritime pine bark extract (Pycnogenol) effectively inhibit alpha-glucosidase. Diabetes Res Clin Pract, 2007. 77(1): p. 41-6.
14. Kwak, C.J., et al., Antihypertensive effect of French maritime pine bark extract (Flavangenol): possible involvement of endothelial nitric oxide-dependent vasorelaxation. J Hypertens, 2009. 27(1): p. 92-101.
15. Xue, B., et al., Effect of total flavonoid fraction of Astragalus complanatus R.Brown on angiotensin II-induced portal-vein contraction in hypertensive rats. Phytomedicine, 2008.
16. Mizuno, C.S., et al., Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARalpha. Bioorg Med Chem, 2008. 16(7): p. 3800-8.
17. Sato, M., et al., Dietary pine bark extract reduces atherosclerotic lesion development in male ApoE-deficient mice by lowering the serum cholesterol level. Biosci Biotechnol Biochem, 2009. 73(6): p. 1314-7.
18. Kimura, Y. and M. Sumiyoshi, French Maritime Pine Bark (Pinus maritima Lam.) Extract (Flavangenol) Prevents Chronic UVB Radiation-induced Skin Damage and Carcinogenesis in Melanin-possessing Hairless Mice. Photochem Photobiol, 2010.
19. Pavlou, P., et al., In-vivo data on the influence of tobacco smoke and UV light on murine skin. Toxicol Ind Health, 2009. 25(4-5): p. 231-9.
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21. Bito, T., et al., Pine bark extract pycnogenol downregulates IFN-gamma-induced adhesion of T cells to human keratinocytes by inhibiting inducible ICAM-1 expression. Free Radic Biol Med, 2000. 28(2): p. 219-27.
22. Rihn, B., et al., From ancient remedies to modern therapeutics: pine bark uses in skin disorders revisited. Phytother Res, 2001. 15(1): p. 76-8.
23. Saliou, C., et al., Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract. Free Radic Biol Med, 2001. 30(2): p. 154-60.
24. Van Wijk, E.P., R. Van Wijk, and S. Bosman, Using ultra-weak photon emission to determine the effect of oligomeric proanthocyanidins on oxidative stress of human skin. J Photochem Photobiol B, 2010. 98(3): p. 199-206.
25. Haskell, C.F., et al., The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol, 2008. 77(2): p. 113-22.
26. Owen, G.N., et al., The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci, 2008. 11(4): p. 193-8.
27. Yamada, T., et al., Effects of theanine, a unique amino acid in tea leaves, on memory in a rat behavioral test. Biosci Biotechnol Biochem, 2008. 72(5): p. 1356-9.
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29. Nathan, P.J., et al., The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother, 2006. 6(2): p. 21-30.
30. Nobre, A.C., A. Rao, and G.N. Owen, L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr, 2008. 17 Suppl 1: p. 167-8.
31. Murakami, S., et al., Effects of oral supplementation with cystine and theanine on the immune function of athletes in endurance exercise: randomized, double-blind, placebo-controlled trial. Biosci Biotechnol Biochem, 2009. 73(4): p. 817-21.
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Stem Cell 100 – Powerful Rejuvenation and Anti-Aging …
Posted: September 2, 2016 at 6:00 am
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Granville Sharp was a civil servant and political reformer. He was one of the 12 men who, in 1787, formed the Society for Effecting the Abolition of the Slave Trade and was the first chairman of the Society. His interest in the issue, however, went back much further.
At a time when most abolitionists argued that the Slave Trade was wrong because of the terrible conditions in whichenslaved peoplewere kept, he (along with Anthony Benezet) went further, arguing that the very nature of slavery itself was evil.
He also used his skills to fight a series of legal battles to preventenslaved peoplebeing taken out of England by force. Many black people resisted enlavement and many escaped from their owners’. However, whether they had escaped, been abandonedor had always been free, they were in constant danger of capture or recapture by slave-hunters’.
In 1767,Granville Sharp and his brother William (a surgeon) helped a badly injured man, Jonathan Strong, whohad been brought to London from Barbados by a plantation owner named David Lisle. Strong had been thrown onto the streets after being beaten about the head with a pistol. He was so badly injured that he was nearly blind and he could hardly walk. They took him to St. Bartholomew’s Hospital. After he regained his health, they helped him to find work as a messenger.
Quite by chance, the man that had assaulted him, saw him and, without capturing him, sold him for 30 to a Jamaican planter. Two slave hunters kidnapped and imprisoned Strong while they waited for a ship to take him to the Caribbean. Strong enlisted Granville Sharp’s help. Sharp demanded that Strong be taken before the Lord Mayor, who declared him a free man.
In 1769, Sharp published his findings in a pamphlet: ‘A representation of the injustice and dangerous tendency of tolerating slavery in England’. Sharp devoted himself to fighting the notion that an enslaved personremained, in law, the property of his master, even on English soil. He did this both by his writings and in the courts of law.
He became the leading defender ofAfrican people in London and saved manyAfrican people from being sent back to slavery in the West Indies, often at his own expense. In 1771 a slave, James Somerset, who had been brought from Jamaica to Britain, ran away. He was recaptured and put on a ship bound for Jamaica. Sharp intervened and put the case before Lord Mansfield, the Lord Chief Justice of England. Sharp hoped this case would finally settle whether it was lawful to hold people as slaves in England and Wales. After many months of legal argument, Mansfield finally decided that a master had no right to force an enslaved person to return to a foreign country. Somerset was freed.
Although this judgment did not actually state that slavery was illegal in England, it laid down the important notion that an enslaved personcould not be forcibly removed fromEngland. London’s African community celebrated this important victory; they had followed the case closely and made sure that there was always an Africandelegation in court.
Sharp was also involved in other legal cases, such as the slave ship Zong(seeThe Middle Passage).Cases such as this help to raise public awareness of the horrors of slavery and started to turn public opinion against the slave trade. In May 1787, he joined with Thomas Clarkson and nine Quakers, to form the Society for Effecting the Abolition of the Slave Trade and continued to work for abolition until the act was passed in 1807. However, Granville Sharp was not to see the final abolition of slavery in the British Colonies, as he died on 6th July, 1813.
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Posted: at 9:19 am
Maximize investment returns while Minimizing risk and Maximize health and longevity in Minimum time. How to Profit from the Coming Revolution in Anti-Aging Science… Even If You Do Not Invest
Why not get involved in an emerging trillion dollar industry… while developing technologies that are designed to extend healthy lifespans by 25 years or more?
My name is David Kekich. I founded and managed the biggest marketing arm of a Fortune 500 life insurance company until an unfortunate accident changed the direction of my life thirty two years ago. (It could also impact your life in a very positive way.)
then, I have devoted myself to a single passion:
I have invested the remainder of my time to say nothing of considerable financial resources to advancing life extension technologies. In other words, I understand the anti-aging industry. Over the past nine years, I helped build a world-class, star-studded scientific team.
As you will see in the following pages, there is a compelling case to be made for the potential rewards for individuals who embrace an appropriate and sound approach to this emerging growth market.
The Next Big Investment Sector Can Make Early Participants Very Wealthy
All it takes is one glance at the chart below to see where the biggest money will be made in the health care field in the years just ahead. Its going to be in treating and preventing diseases and conditions related to AGING.
U.S. Population Aged 80+
It is still some time before Wall Street will put the full force and power of their resources behind solutions to the aging problem.
But now, a world-class investment management team headed by the former CEO of Citicorps pioneer venture group (he built it into a $50 million fund that earned over $7 billion) has set its sights on the opportunity.
And the opportunity for you reading this Special Report today is twofold, because:
1) You can be part of an elite inner circle who are on the cutting edge of information and treatment as research postpones the debilitating effects of aging by years or even decades; and
2) You can participate financially with a group of unusually dedicated and extraordinarily credentialed investment professionals as they pursue maximum returns in this exploding field of research and development.
The prize is a longer and healthier life, coupled with what could become the most important and exponentially lucrative investment youve ever made.
Aging: An Impossible Problem. Or the Ultimate Opportunity?
We all consider aging to be lifes ultimate reality. On our birthdays, our friends often joke with us that its better than the alternative! Thats because, all our lives (and all throughout human history up to this point), there has been no alternative to aging and the symptoms and diseases of aging. But you and I are fortunate to be living at the precise moment in history when mankind is experiencing a veritable explosion of science and technology. Our entire world is changing virtually every day due to exciting, breakthrough innovations in every industry from telecommunications to travel from computers to cars from farming to pharmaceuticals and everything in between. But nothing is more exciting, in my view, than the technological advances that have already been made (and continue to be made nearly every day) in the rapidly growing science of anti-aging. What Does Anti-Aging Really Mean? First of all, dont let the term anti-aging (as its used and abused today) fool you. The science-based anti-aging industry emerging today is qualitatively different. It targets products that will substantially extend lifespan as well as make that lifespan healthier even for those with all the right lifestyle habits including eating right and exercising regulary with these Muscle Building Workouts. Today anti-aging is already a multi-billion dollar business even though most of the products have little or no basis in medical science. Many promoters mislead, exaggerate and make false claims to sell to a market eager to hang on to their youth. The anti-aging were talking about isnt about snake oil; its about the emerging (and serious) field of life-extension medicine. Anti-aging science is quickly coming of age and being taken very seriously by esteemed universities, respected research institutions, and giant pharmaceutical companies. Breakthroughs in Life Extension Are Already Here In fact, some new inventions and innovations in anti-aging medicine have already proven themselves behind the closed doors of our nations top research and testing agencies. Theyre already here. They just havent been released yet to the general public. Thankfully, however, many of these breakthroughs dont take as much time as do other health care innovations, such as new drugs. And because of the rapidly approaching urgency and the looming, overwhelming demand for anti-aging innovations, were soon going to see wave after wave of anti-aging products getting introduced to a TRILLION-DOLLAR world market of people who are literally dying to hold onto their health, youth, beauty and vitality. Its what we all want, actually. And now, thanks to the unique research and marketing strategy weve developed here at Maximum Life Foundation, you can learn about the development and distribution of the very innovations that will one day very soon benefit you directly and help you lead a longer, healthier, wealthier and happier life. SAP Training – Training and certification in over 30 different SAP career paths.
This white paper will take you on a journey into the exciting world of anti-aging science and show you the virtually unlimited opportunities that await savvy people like you who get on board the train to the future and do it now.
Welcome aboard. David A. Kekich President, Maximum Life Foundation January 2010
One final note before we begin: I want you to know that nearly all of my personal financial return from my activities goes to The Maximum Life Foundation. In other words, Im in this for the money but not the way you think.
Special Report on Life Extension Technology By David A. Kekich
AGING: A Growing Problem Becomes an Enormous Opportunity
Its happening all over the world
Imagine the potential profit if you participated in even one of these! And our research is uncovering dozens of similar opportunities. Its no accident venture capitalists and major medical companies are investing billions of dollars annually in research leading toward the treatment and cure of incurable diseases. Why? They readily recognize the upside to such investment. Today, the biggest returns both to investors and to individuals who want to live longer, healthier, and therefore more productive lives will come in the field of anti-aging medicine. And heres why: Back in the year 2000, the number of Americans (for example) aged 65 or older reached an estimated 35 million and accounted for almost 13 percent of the total U.S. population. The rapidly aging U.S. population is very significant especially when you consider the number of older Americans has increased more than ten-fold since the turn of the last century. This trend is mirrored in other developed countries. And, its projected to accelerate even faster over the next 30 years. This is both a problem and an opportunity. Its a problem because the diseases associated with aging will put a tremendous burden on our health-care system (along with the younger taxpayers who will have to foot the bill).
The table below lists just a few of the adverse health events that our older population is now experiencing
Health events that increase with aging
These aging-dependent chronic diseases and conditions are now the most common forms of illness in the United States. Heart disease and stroke alone account for almost 40% of all deaths.
Consider this chart
Altogether, the groups of degenerative diseases we link to aging are directly responsible for the deaths for roughly 75% of all deaths in the United States.
Whats more, the list of diseases above has contributed to a quadrupling of health care expenditures per person in the U.S., rising from $1,067 in 1980 to $4,358 in 1999.
By 2010, those expenditures are expected to double again. Total national health expenditures are projected to equal $2.6 trillion and reach 15.9 percent of the Gross Domestic Product by 2010, up from 13 percent in 1999.
Its pure demographics. You see, the burgeoning number of baby boomers in our society will begin to turn 65 in 2011. And by 2030, the proportion of the population 65 or older will be one in five or 70 million U.S. citizens.
In the United States, the population 80 and older is currently 9.2 million (3.35 percent of the U.S. population). This age segment is projected to grow to 14.9 million (4.4 percent of population) by the year 2025 and to 31.6 million (7.82 percent of population) by the year 2050.
In other industrialized countries around the world, the percentage of the population age 65 or older is even higher than in the U.S. The percentage of population over 65 in the United Kingdom, Italy and Japan is 24%, 44% and 34% higher than in the United States, respectively.
This is truly a growing problem, worldwide. And it cries out for a solution.
Fortunately, timing is on our side because science MAY NOW HAVE solutions to some of the age-related diseases listed above.
Happily, the catastrophic effects of such a huge percentage of our population getting old and getting sick all at the same time can now be virtually eliminated IF the science of anti-aging proceeds on the fast track and quickly develops the treatments and cures to life-threatening (and life-shortening) diseases we now passively accept.
And thats what we at the Maximum Life Foundation are all about: Helping to get anti-aging science into the mainstream before its too late for you.
Whether youre young or old, herein lays one of the major investment opportunities of the 21st century.
ANTI-AGING MEDICINE: An Emerging Solution
Think about it
If the illnesses and deaths weve been talking about were preventable, shouldnt we stop them if we can?
Let me put it another way: If a loved one (or yourself) had a major medical condition such as cancer, heart disease or suffered a stroke., wouldnt you ask that they (or you) receive the very best medical care for those conditions?
If there was a treatment that could reverse Alzheimers, Parkinsons, osteoporosis, arteriosclerosis or diabetes who in their right mind would turn it down?
What ties all these diseases together is the underlying processes of aging.
But now, science is gradually coming to the realization that aging itself could be classified as a disease. Why? Because its not necessarily normal or inevitable for the bodys vital organs to stop functioning properly. Scientists now know that our cells could live and grow in the same healthy manner as when we were in our 20s!
Am I just blowing smoke?
Heres the hard-core evidence that gives everyone involved in anti-aging science so much cause for optimism
How the EXPLOSION of Scientific Progress Is Revolutionizing Our Lives
To properly understand what Im about to share with you, you need to know that the pace of scientific advancements today far outstrips what you and I have been accustomed to during our lifetime.
Whereas science used to proceed at a snails pace, thats not the case anymore. Now its approaching the speed of light!
Its all because several sciences and technologies are finally coming together and working synergistically on the problems that face mankind.
For instance, medical researchers are now able to use supercomputers to speed up experiments that used to take years. The key? Theyre using a new technology known as bioinformatics.
Bioinformatics is a computer-assisted data management discipline that assists in accumulating, analyzing and representing biological processes. Emerging in the 1990s, this field is accelerating the drug discovery and development process through in vitro (in test tubes) and in vivo (in animals or humans) testing processes. Now theyre adding in silico (computer simulations) to turbo charge anti-aging science.
The major task of bioinformatics is utilizing the power of supercomputers to convert the complexity of the genetic codes of the human genome into useful information and knowledge that can be harnessed to understand the aging process and its attendant diseases.
The result? Faster and faster progress in the anti-aging sciences
Its not a surprise. In the modern era, our knowledge has been advancing by quantum leaps compared to most of human history. For instance, scientific knowledge doubled from the year 1 A.D. to 1500 A.D. But by 1967, it doubled five more times… and each time, faster than before.
And several experts estimate that today, biotech knowledge doubles about every 48 months. Some computer scientists project that by 2010, scientific knowledge in general will double every 100 days!
Part of the reason? As I said, supercomputers, like the kind now being used in bioinformatics. These computers can do experiments in 15 seconds that used to take years. Its no wonder were gaining on the aging problem so fast!
Heres another anti-aging advance: Newly developed research tools called gene chips can do tissue studies in hours or even minutes that used to take years of animal studies. These gene chips are actually laboratories on a chip. Theyre simply amazing.
But perhaps the most profound observation is the rate of change itself is accelerating. This means the past is not a reliable guide to the future. The 20th century was not 100 years of progress at todays rate but, rather, was equivalent to about 20 years, because weve been speeding up to current rates of change. And, well make another 20 years of progress at the year 2000 rate, equivalent to that of the entire 20th century, by 2014. Then well do it again by 2021.
Because of this exponential growth, the 21st century will equal 20,000 years of progress at todays rate of progress 1,000 times greater than what we witnessed in the 20th century, which in itself was no slouch for change.
And youre probably aware that the power of technology per dollar doubles every 12 months. This means our tools could be 1,000 times more powerful in just 10 years and a billion times more powerful by 2035.
On top of that, scientists just launched an emerging discipline known as nanomedicine that will revolutionize cell repair.
In a nutshell, nanomedicine, the medical application of nanotechnology, could eventually build or repair almost every cell in the body, from the bottom up, atom-by-atom. It promises to give us complete control of matter and a very efficient way to cure aging damage, injuries and diseases.
More Anti-Aging Breakthroughs
For your information, here are some of the anti-aging and life-extension breakthroughs that took place just in the last few years
That means someday, we could completely understand how the human body works at the most basic level. This will greatly speed up the time it takes to develop new treatments for all diseases.
By understanding how eating less calories works to extend life in something like yeast, scientists can use this information to figure out the same pathway in humans. Then, we could develop drugs to do the same thing. In fact, Dr. Guarente co-founded Elixir Pharmaceuticals to do just that, and now, several caloric restriction mimetics have been discovered.
This is the first time drugs dramatically extended the lifespan of a complex form of life. This could perhaps result in a pill that would greatly extend your lifespan and your healthspan.
Once again, turning the right genes on or off can extend lifespan.
Stem cell research could eventually lead to a cell-by-cell replacement of the human body, substituting old cells with new young cells.
With good gene therapy techniques, the same type of thing might add about 30 years to our lives. Thats not an exaggeration.
Resveratrol is now available as a supplement for human consumption.
Recently, a group at the University of Wisconsin developed a technique to locate many genes that are involved in the aging process in mice. This may soon allow us to control the aging process itself.
At Sierra Sciences, a biotechnology company, researchers have been working on shutting off the cellular aging clock, the telomere.
There are far too many examples to list them all.
What does all this research mean?
Very simply this: With todays astonishing pace of scientific progress, well most likely develop technologies in the next 5 to 10 years in the lab that could eventually slow aging to a crawl.
Maybe halt it.
Maybe even reverse it by 2029.
And even before these technologies are translated to humans, they will be worth BILLIONS.
Where the Money Will Be Made in Life Extension Technology
Aside from the sheer humanitarian benefits of anti-aging science and the promise of a disease-free, healthy and happy society, theres also a lot of money to be made in this sector for those who are savvy enough to see the trend and invest early.