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Eczema – National Library of Medicine – PubMed Health

Posted: September 11, 2016 at 5:19 pm

Evidence reviews Effects of antihistamines on eczema

Eczema is a common chronic disease. Itch is the most important symptom, and eczema is often accompanied by dry skin. Skin lesions include rash, redness, swelling of the skin, crusts, oozing, and sometimes also bleeding as a consequence of persistent scratching. Although the disease can resolve during childhood, it might also recur in or persist into adult life. The cause of eczema is considered to be a combination of genetic and environmental factors. Moisturisers, topical corticosteroids, and topical immunomodulators are the mainstay during treatment of eczema, while more severe cases might need UV light therapy or systemic immunosuppressants. Itch is very difficult to treat and leads to scratching, which leads to more inflammation of the skin, and often people with eczema end up in a vicious circle of itching and scratching. The role of histamine in itching associated with eczema is not fully elucidated, but oral H1 antihistamines have been used for many years in the treatment of eczema. These might have been used largely for their sedative action, with highly sedative antihistamines, e.g. chlorpheniramine and hydroxyzine. However, oral H1 antihistamines are widely used in the treatment of allergic disorders, such as urticaria, allergic rhinitis, and allergic conjunctivitis, but their efficacy in alleviating itch and eczema remains unclear. This systematic review sought evidence for the effects and safety of the use of oral antihistamines for eczema, to guide their use in clinical practice.

Atopic eczema (atopic dermatitis or childhood eczema) is a big problem worldwide. The skin of people with atopic eczema often contains high numbers of a bacterium called Staphylococcus aureus (S. aureus).

This review of clinical trials aimed to find out whether topical pimecrolimus is better than topical corticosteroids or tacrolimus for treating eczema in infants, children and adults by assessing the improvement of eczema and adverse events associated with treatments.

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Eczema is a common chronic disease. Itch is the most important symptom, and eczema is often accompanied by dry skin. Skin lesions include rash, redness, swelling of the skin, crusts, oozing, and sometimes also bleeding as a consequence of persistent scratching. Although the disease can resolve during childhood, it might also recur in or persist into adult life. The cause of eczema is considered to be a combination of genetic and environmental factors. Moisturisers, topical corticosteroids, and topical immunomodulators are the mainstay during treatment of eczema, while more severe cases might need UV light therapy or systemic immunosuppressants. Itch is very difficult to treat and leads to scratching, which leads to more inflammation of the skin, and often people with eczema end up in a vicious circle of itching and scratching. The role of histamine in itching associated with eczema is not fully elucidated, but oral H1 antihistamines have been used for many years in the treatment of eczema. These might have been used largely for their sedative action, with highly sedative antihistamines, e.g. chlorpheniramine and hydroxyzine. However, oral H1 antihistamines are widely used in the treatment of allergic disorders, such as urticaria, allergic rhinitis, and allergic conjunctivitis, but their efficacy in alleviating itch and eczema remains unclear. This systematic review sought evidence for the effects and safety of the use of oral antihistamines for eczema, to guide their use in clinical practice.

Probiotic supplements for pregnant women and babies can prevent the development of eczema in some children. Probiotics have been better researched than prebiotics.

Atopic eczema (atopic dermatitis or childhood eczema) is a big problem worldwide. The skin of people with atopic eczema often contains high numbers of a bacterium called Staphylococcus aureus (S. aureus).

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Eczema – National Library of Medicine – PubMed Health

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About Eczema – What is Eczema?

Posted: at 5:19 pm

Eczema refers to a chronic inflammatory skin condition, characterized by dry skin, with patches that are red and intensely itchy. These patches of eczema may ooze, become scaly, crusted, or hardened. Symptoms can range from mild to severe, and the condition can negatively impact quality of life. Eczema can occur anywhere on the skin and is commonly found on the flexors (bends of the arms, backs of the knees).

There are many types of eczema, with the most common one being atopic dermatitis. Atopy refers to a hereditary tendency toward eczema, asthma, and allergic rhinitis (hay fever). People with eczema may suffer with one of the other atopic diseases.

The exact cause of eczema is unknown, however, there are genetic, immunological and environmental factors that play a role. Eczema can come and go, and can migrate around the body; just as one patch clears up, another may develop. This is the chronic nature of the disease. When the skin cycles back to inflammation, the patient is experiencing a flare-up.

Atopic eczema is the most common form of eczema and is closely linked with asthma and hayfever. It can affect both children and adults, usually running in families. One of the most common symptoms of atopic eczema is itching (pruritus), which can be almost unbearable. Other symptoms include dryness of the skin, redness and inflammation. Constant scratching can also cause the skin to split, leaving it prone to infection. In infected eczema the skin may crack and weep and develop pustules. Treatments include emollients to maintain skin hydration and steroids to reduce inflammation.

ACD develops when the bodys immune system reacts against a substance after contact with the skin. The allergic reaction often develops over a period of time through repeated contact with the substance. For example, an allergic reaction may occur to nickel, which is often found in earrings, snaps on baby’s undershirts, belt buckles and jean buttons. Reactions can also occur after contact with other substances such as perfumes and rubber. In order to prevent repeated reactions it is best to prevent contact with anything that you know causes a rash.

This is a type of eczema caused by frequent contact with everyday substances, such as detergents and chemicals, which are irritating to the skin. It most commonly occurs on the hands of adults and can be prevented by avoiding the irritants and keeping the skin moisturized. It commonly occurs in patients who have atopic dermititis.

A condition that affects babies under one year old, the exact cause of which is unknown. Also referred to as cradle cap, it usually starts on the scalp or the nappy area and quickly spreads. Although this type of eczema looks unpleasant, it is not sore or itchy and does not cause the baby to feel uncomfortable or unwell. Normally this type of eczema will clear in just a few months, though the use of moisturising creams and bath oils can help to speed this along.

Characteristically affects adults between the ages of 20 and 40. It is usually seen on the scalp as mild dandruff, but can spread to the face, ears and chest. The skin becomes red, inflamed and starts to flake. The condition is believed to be caused by a yeast growth. If the condition becomes infected, treatment with an anti-fungal cream may be necessary.

Varicose eczema affects the lower legs of those in their middle to late years, being caused by poor circulation. Commonly the skin around the ankles is affected, becoming speckled, itchy and inflamed. Treatment is with emollients and steroid creams. If left untreated, the skin can break down, resulting in an ulcer.

Is usually found in adults and appears suddenly as a few coin shaped areas of red skin, normally on the trunk or lower legs. They become itchy and can weep fluid. Usually discoid eczema is treated with emollients (and steroid creams if necessary).

Some complications of eczema include skin infections, eczema herpticum, neurodermatitis, and eye complications.

Scratching that is associated with eczema can break the skin causing open sores which can then become infected. This can cause mild or more serious infections. See a physician if there is swelling, pain, crusting, or oozing of the eczema.

Skin that becomes inflected with the herpes simplex virus (the virus that causes cold sores) is called eczema herpeticum. The symptoms may include painful pus or fluid filled blisters or sores, which may be accompanied by fever, tiredness, and swollen glands. Prompt treatment is very important, as the inflection can spread to the eyes or internal organs, causing serious problems.

Caution should be taken around anyone with a cold sore; kissing and skin-to-skin contact should be avoided. Take extra caution with infants and children, especially those with eczema and/or open areas on their skin. Sometimes, with infants and small children, contact with the herpes simplex virus can be fatal. See a doctor immediately if there are concerns.

Long term itching and scratching of the skin can lead to an increased sensation of itch, which could possibly lead to neurodermatitis (also known as lichen simplex chronicus). These areas of the skin that are frequently scratched become thick and leathery in appearance, and the patches can be red and darker than the rest of the skin. Persistent scratching can lead to permanent changes in skin colour. See a physician if experiencing intense itch and/or there are noticeable changes in the skin.

In rare cases, severe atopic dermatitis can lead to eye complications which could potentially cause permanent eye damage. See a physician if experiencing eye watering, inflammation around the eye, and eye discharge.

Our skin is the barrier to the outside world, is somewhat waterproof, and keeps our internal organs and systems safe from the elements and from bacteria invading our bodies. Atopic dermatitis patients have impaired barrier function. This means that the skin barrier is broken down, loses moisture, and can allow bacteria to grow and enter the body (causing bacterial infections on the skin). The loss of water leaves the skin dry and cracked. The goal of eczema management is to replenish moisture, and create a barrier to protect the skin. This is why moisturizers can help.

Flare-ups can be prompted by environmental elements or triggers such as certain soaps, clothing fabrics, deodorants, carpet fibres, dust, and others. Sometimes a flare-up will occur, however, with no discernible trigger. Overheating, excessive sweating, low humidity, certain foods and stress can also contribute to flare-ups. When the skin becomes irritated by any one of these irritants, it itches, causing the sufferer to scratch the affected area. Scratching makes the condition worse and the skin becomes inflamed and reddened, aggravating the itch. This is called the itch-scratch cycle and can become severe and cause pain.

Look around you and write down all of the possible things in your surroundings that could be contributing to your flare-ups. For example, do you experience a flare-up or worsening of your eczema when you wear a certain sweater? Is your eczema worse in the winter? Do you itch on the days when you clean your house? Does perfume irritate your skin? Use this trigger chart to help to identify your triggers.

Controlling factors in your environment can help minimize flare-ups from occurring. By minimizing or eliminating your triggers, you can help to reduce the number of flare-ups experienced. One of the frustrating parts of eczema is that flare-ups can still occur even when you are diligently avoiding triggers and taking care of your skin. Keeping your skin moist is your first line of defence against eczema.

Certain foods can trigger a flare-up, just like other environmental triggers. This can occur by eating the trigger food, or by skin contact with the food during preparation or during eating (on the hands and around the mouth). It is important to note that food allergies do not cause eczema, however foods can trigger a flare-up. It is not recommended to withhold foods, or entire food groups, for long periods of time without consulting your doctor or your allergist to confirm that there is in fact an allergy to that food. Allergy skin testing can help to provide clues about environmental and food allergies, however patients with atopic dermatitis have high false positive rates, as the simple act of scratching the skin during testing can cause inflammation which may then be misinterpreted as an allergic reaction. Antihistamine use can also impact the accuracy of allergy testing. Speak with your allergist about your eczema, and your medical treatments prior to testing.

Atopic eczema is a chronic, recurring condition with “flares” (active or new patches of eczema which look red, scaly, and/or bumpy) and remissions (when eczema is not as active). Some people always seem to have some active areas. There are no definite cures for eczema although patients can achieve excellent control and live quite comfortably. Most children will grow out of their eczema, and flares will gradually reduce over time. We recommend following our Triangle of Control (LINK) and Regimen (LINK) to ease your eczema symptoms and prevent future flares. This is the first line of defence!

When one member of the family suffers with eczema, the whole family suffers. Rigorous bathing and moisturizing regimens, constant monitoring of the condition, lifestyle changes in an effort to avoid triggers, and sleepless nights can greatly impact the quality of life for all members of the family.

Talking with others who understand what you are going through is very important. Eczema is a spectrum disease, meaning that there are very mild conditions which are not bothersome to the patient, and then there are moderate and severe conditions that have significant physical and psychological impacts. Often the impact of eczema is minimized.

Eczema has a significant psychological impact on sufferers and their families.

Eczema impacts quality of life for the sufferer and their whole family. Social interactions, relationships, work, family, comfort, and self-image can all be negatively affected when eczema is not well controlled.

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Best On Bahamas | Great Things To Do In The Bahamas

Posted: September 3, 2016 at 11:43 pm

Welcome to Best On Bahamas, the premiere destination for things to do in the Bahamas. We only offer top quality tours, activities and shore excursions. We offer things to do in Nassau Bahamas and Freeport Bahamas. The Bahamas offers pristine beaches and dazzling coral reefs all surrounded by the beautiful turquoise waters and unique marine life. Whether it’s your first time visiting The Bahamas or you are returning for more, we want to be your Insider to the wonderful activities these islands have to offer. Let Best On Bahamas and our staff be your guide to the perfect Bahamas Vacation, helping you with everything from the best time to go, cruise excursions and information, hotels, and other insider tips on things to do in the Bahamas.

There are more than enough fun things to do to keep you and your family occupied on your Bahamas vacation. We recommend starting off your island vacation with the Biking, Shopping, and Beach Tour to familiarize yourself with the islands, meet and greet with the locals live. Get some souvenir shopping done and get your exercise for the day in as you bike behind your guide to the beach.

For the adults that want to get away from it all for some fun and dancing should take a look at the Bonfire on the Beach. Guests get to watch the sunset and spend the twilight hours next to the bonfire on the beach while sipping on drinks, and eating Bahamian cuisine, then dance the night away with new friends. If you are a person who would rather venture into the whimsical, and untouched forest of the Bahamas, then your route is going toward the Lucayan National Park and Cave tour. With this, you get the chance to be guided through the caves and the forest that the Lucayans once walked amongst.

There are so many choices when it comes to doing anything aquatic in the Bahamas. One of the most popular activities for visitors of the Bahamas to participate in are snorkeling tours. Of course, there are many to choose from, so we here at Best On Bahamas want to help you save time. One of our most popular things to do is the Bahamas Booze Cruise, which takes its passengers out on a 45-foot catamaran to a deserted island for a beach party, and crystal clear waters for snorkeling. Want to really enjoy your Bahamas vacation the Caribbean way? Jump aboard the Barefoot Sailing All Day Island Cruise, which will take passengers to rarely seen snorkeling spots. Give yourself a real, once-in-a-lifetime chance to encounter one of the most intelligent mammals on Earth, the Atlantic Bottlenose Dolphin. The Blue Lagoon Dolphin Close Encounter gives patrons the opportunity the get up close and personal with dolphins of the famous Blue Lagoon. Take it a step further and sign up to swim with the dolphins with the Blue Lagoon Swim with the Dolphins program.

Whether your boating trip goals are to fish the deep blue sea for your dinner, sail around the crystal clear waters, or cruise at the fastest speeds you’ve been on a boat across the ocean waves, there is something for everyone’s preference for their vacations.

The historic city of Nassau is the capital city of the Bahamas. It is a wildly popular tourist destination, both as a port of call for cruise ships and for those looking for a relaxing, exciting, and luxurious vacation. The city is filled with activities to enjoy both during the daytime and at night, and is home to some of the finest resorts anywhere. It is a vibrant mix of the Old World and modern times. Once a haven for pirates and vagrants, Nassau now exudes charm beyond compare especially with its various tours and activities.

Freeport is located on Grand Bahama Island, the fourth largest island of the Bahamas that is second in popularity only to Nassau as a tourist destination of the Bahamas. Located approximately 70 miles off the southeastern coast of Florida, Grand Bahama Island is a tropical paradise that only seems out-of-the-way. Because Grand Bahama Island is larger than New Providence Island (the home of Nassau), there are more lengths of secluded white sand beaches to relax and play on. Freeport and all of Grand Bahama Island is a bold island paradise with modern attitude mixed with a little colonial charm, and will provide endless opportunities for adventure and fun, especially with Freeport tours.

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Life Extension – Page 1 – Health Food Emporium

Posted: August 12, 2016 at 2:38 pm

Sort by: Sort by Featured Items Newest Items Bestselling Alphabetical: A to Z Alphabetical: Z to A Avg. Customer Review Price: Low to High Price: High to Low Sort by: Sort by Featured Items Newest Items Bestselling Alphabetical: A to Z Alphabetical: Z to A Avg. Customer Review Price: Low to High Price: High to Low

The Life Extension Foundation was the first organization to defy the FDA by promoting the use of antioxidant vitamins to maintain health.

Life Extension uses only premium quality vitamins and other ingredients. Their dedication to excellence insists that their nutritional supplements meet the highest standards and criteria. That is why Life Extension insists on purchasing only the highest quality raw materials from all over the world, primarily from leading US, Japanese and European sources. The unique ingredients included in Life Extensions products are often years ahead of the products sold by commercial vitamin companies.

Blueberry Extract with Pomegranate 60 capsule $30.00 $22.50

Life Extension Blueberry Extract with Pomegranate When scientists analyze fruits and vegetables for their antioxidant capability, blueberries rank among the highest in their capacity to destroy free radicals. Rich in…

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Bone Restore (Without K) 120 Capsules $22.00 $16.50

Throughout life, cells known as osteoblasts construct bone matrix and fill it with calcium. At the same time, osteoclasts work just as busily to tear down and resorb bone. This fine balance is regulated by many factors,…

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Calcium Citrate with Vitamin D 300 Capsules $24.00 $18.00

Calcium is the most abundant mineral in the body …primarily found in the bones and teeth. In bone formation, calcium forms crystals that provide strength to maturing bone. Calcium is needed for more than just healthy bones…

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Cognitex with Brain Shield 90 Soft Gels $60.00 $45.00

Life Extension Cognitex with Brain Shield Complex Protecting brain health is vital if the pursuit of a longer life is to have any meaning. According to current wisdom, some degree of cognitive impairment is all but…

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Cognitex with Pregnenolone 90 Softgels $62.00 $46.50

Brain decline affects all aging humans. Scientific studies demonstrate more youthful cognition and memory in response to the proper nutrients. Cognitex provides the following brain boosting ingredients in one advanced…

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Cognizin CDP Choline 250 mg 60 Capsules $36.00 $27.00

Choline is a substance needed by the brain to produce acetylcholine, a major brain/motor neuron neurotransmitter that facilitates the transmission of impulses between neurons. The importance of choline for maintaining…

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D-Ribose 100 Vegetarian Tablets $32.00 $24.00

Life Extension D-Ribose 120 vegetarian capsules People suffering from cardiac and other debilitating health problems often exhibit severely depleted cellular energy in heart and muscle tissue, which can greatly impair normal…

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Enhanced Super Digestive Enzymes 60 Veg Capsules $22.00 $16.50

Life Extension Enhanced Super Digestive Enzymes The aging process and certain health issues cause a reduction in the bodys enzyme production. One effect of this reduction is a bloated feeling soon after eating a large meal…

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FLORASSIST Oral Hygiene Probiotic 30 lozenges $20.00 $15.00

Florassist is Probiotics for the mouth. Oral health disorders are among the most common health problems in US adults. Regular brushing and flossing is often not enough to achieve optimal oral health. Since the mouth is the…

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Glucosamine Chondroitin 100 Capsules $38.00 $28.50

Life Extension Glucosamine Chondroitin Capsules A naturally occurring amino sugar synthesized in the body from L-glutamine and glucose, glucosamine stimulates the manufacture of glycosaminoglycans, important components of…

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Immune Protect With Paractin 30 capsules $29.50 $22.13

Life Extension Immune Protect With Paractin Immune Protect with PARACTIN contains a combination of patented ingredients that have been clinically shown to boost immune function, increasing the bodys natural ability to combat…

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Integra Lean African Mango Irvingia 60 Veg Caps $28.00 $21.00

Life Extension Integra-Lean Irvingia 150mg, 60 Vegetarian Capsules Scientists have identified specific biological mechanisms that cause aging people to gain weight no matter how little they eat. The problem was that there…

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MacuGuard Ocular Support 60 Soft Gels $22.00 $16.50

Life Extension MacuGuard Ocular Support The eye is a highly complex organ that must safely harvest, control, focus, and react to light in order to produce vision. Light enters the anterior portion of the eye through the…

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MacuGuard Ocular Support with Astaxanthin 60 Softgels $42.00 $31.50

Lutein is one of the major components of macular pigment and it is essential to proper vision.1 Eating large quantities of lutein and zeaxanthin-containing vegetables can help provide the nutritional building blocks…

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Magnesium 500 mg 100 Capsules $12.00 $9.00

Many Americans do not obtain adequate amounts of magnesium in their diets. Magnesium is one of the bodys most important minerals. It is required as a cofactor in hundreds of enzymatic processes within cells. It helps…

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Magnesium Citrate 160 mg 100 Capsules $9.00 $6.75

Many Americans do not obtain adequate amounts of magnesium in their diets. Magnesium is one of the bodys most important minerals. It is required as a cofactor in hundreds of enzymatic processes within cells. It helps…

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Melatonin 10 mg 60 Capsules $28.00 $21.00

Life Extension Melatonin 10 mg capsules Melatonin releases from the pineal gland, reaching its peak at night to help maintain healthy cell division in tissues throughout the body. Secretion of melatonin declines…

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Melatonin 3 mg 60 Capsules $8.00 $6.00

Life Extension Melatonin 3 mg capsules Melatonin releases from the pineal gland, reaching its peak at night to help maintain healthy cell division in tissues throughout the body. Secretion of melatonin declines significantly…

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Mitochondrial Energy Optimizer with BioPQQ 120 capsules $94.00 $70.50

All cells in our bodies contain tiny organelles called mitochondria that function to produce cellular energy by means of the adenosine triphosphate (ATP) cycle. The number of mitochondria in a cell varies widely by organism…

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Mix 315 Tablets $80.00 $60.00

Numerous scientific studies document that people who eat the most fruits and vegetables have much lower incidences of health problems. Few people, however, consistently eat enough plant food to protect against common…

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Home – Oceania

Posted: July 23, 2016 at 4:22 am

Welcome to Oceania Cruises

Your World. Your Way.

Filled with a spectacular array of diverse and exotic destinations, your world awaits your discovery. There is simply no better way to explore it than aboard the elegant ships of Oceania Cruises. Our unique itineraries are handcrafted, featuring the most fascinating destinations throughout the world. As Regatta, Insignia, Nautica, Sirena, Marina and Riviera are all comfortably mid-size, each ship calls on the worlds most desirable ports, from historic cities and modern meccas to charming seaside villages and faraway islands. On a voyage with Oceania Cruises, each day offers the rewarding opportunity to experience the history, culture and cuisine of a wondrous new destination.

Relax on board our luxurious ships and savor exquisite cuisine that not only is renowned as the finest at sea, but also rivals the best restaurants ashore. Inspired by Master Chef Jacques Ppin, these culinary delights have always been a hallmark that distinguishes the Oceania Cruises experience from any other. Considering the uncompromising quality, perhaps the most remarkable aspect of an Oceania Cruises voyage is its incredible value. Lavish complimentary amenities abound, and there are never supplemental charges in any of the onboard restaurants. Value packages ensure that sipping a glass of vintage wine, surfing the Internet or enjoying a shore excursion is both convenient and affordable.

As the leader in destination cruising, Oceania Cruises sails to more than 330 ports around the globe. Itineraries are unique in that they call on the perfect mix of must-see marquee and boutique, off-the-beaten-path ports. Multiple overnight calls afford an in-depth, enriching destination experience and allow travelers to immerse themselves in the cuisine, culture and history of the ports we visit.

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Offshore Jobs | $69,999+ Pay Possible | #1 Trusted …

Posted: July 16, 2016 at 11:15 pm

Offshore oil rig jobs are great way to play an important role in the global energy business. If want to work in an office were you get to watch the sunset and feel the ocean breeze every day and make a ton of money while doing it then a drilling platform is a place for you. Find out how to get hired for oil rig jobs here.

Oil and gas play a giant role in Louisiana. With many offshore drilling companies located here, you can find many offshore jobs in Louisiana. Read this article to find out more about your options and how to get started soon.

If you are really serious about working on an oil rig but have no previous experience in the oil industry this is for you. Roustabout jobs can be dirty and hard but if you are man to take this opportunity, theres simply no better way to learn from the ground floor.

Oil and gas jobs put you in the forefront of the global energy industry. Even though alternative fuels are gaining strength, the fact is oil and gas are going to be dominant energy source for decades to come. Now is the time to find employment in this amazing field.

Are you ready to make some good money in one of the most exciting industries on earth? If you dont mind getting your hands dirty there are always roughneck jobs available for you. Find out more about how your next job could be on an offshore oil platform.

Have you ever work on a oil drilling crew before? Are you looking for the ultimate job adventure? If so, find out how offshore drilling jobs are right for you.

Offshore catering jobs are a great way to use your cooking skills. Plus, youll make more than you ever would at most restaurants on land. Find all the latest offshore catering jobs like cook, baker, and steward here.

Are you a good welder? Looking for an exciting job? Then if youre ready to make good money using your skills in one of the most exciting industries on earth, read as to find out how offshore welding jobs are just the thing for you.

Entry level offshore jobs are many peoples foot in the door in this amazing industry. For those of you just starting out it can be tough, but dont give up. This industry is always willing to give a good, honest worker a fair shot.

Everyday thousands of people go to work on a drilling rig. Would you like to be one of them? There are so many different drilling rig jobs available it helps to know where your skills will fit in. Read this to find out what job opportunities there are for you offshore.

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Ethos – NEUROHACKER COLLECTIVE

Posted: July 14, 2016 at 4:28 pm

Community Forum

Were part of a robust community of neurohackers with backgrounds in neuroscience, cognitive psychology, smart drugs and nootropics, integrative medicine, bioethics, and private laboratory experimentation.

Aligned with our mission of curating the most meaningful neurohacks, were developing an online hub for our peers to answer questions, give input, and share experiential research on the most promising technologies currently available.

Many incredible technologies exist for enhancing our subjective experience, but most people have never heard about them and likely wouldnt stumble upon them through a typical google search. We want to change that.

We are taking on the challenge of curating a directory of the most effective and promising neurohacking technologies and tools out there. That includes anything that influences the neurologic hardware responsible for mediating our conscious experience and performative capabilities: chemical technologies like nootropics and smart drugs, bioelectrical technologies like transcranial stimulation, photic therapies like low level laser therapy, all the way to neurofeedback techniques, meditation training, or embodied practices like somatics.

Our goal is to broadly cover the various categories of technologies that meet our criteria for neurohacks, then hone in on a vetted list of tools and practices weve discovered that produce the most significant positive results. As new discoveries and breakthroughs are made, well work with the community to keep this resource continually updated.

Citizen science and the quantified self movement have opened new portals for discovery, empowering us to collect and analyze data about ourselves, and share what works and what doesnt with each other.

In that spirit, were developing an app to help track changes in psychological states and cognitive capacities, as a function of using our products or any other neurohacking technologies. The data generated will help us better understand the most effective ways to positively influence our neurology to experience a higher quality of life.

Lets just say, cognitive enhancement is only the beginning.

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Ethos – NEUROHACKER COLLECTIVE

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Life Extension Mix Tablets, 315 tablets

Posted: July 9, 2016 at 8:09 pm

Numerous scientific studies document that people who eat the most fruits and vegetables have a lower incidence of health problems. Few people, however, consistently eat enough plant food to provide vital phyto-protection against common age-related decline. Commercial multivitamins do not contain all of the vital plant components needed to maintain good health.1-3

Life Extension Mix is vastly superior to other multivitamins on the market todaypartly because it provides a remarkably broad array of fruit and vegetable extracts.

Packed into this blend are extracts of fruits ranging from grape and maqui to bilberry and tart cherry. Its standardized vegetable extracts range from broccoli to artichoke. All with known health benefits throughout the body.

Rounding out the superiority of Life Extension Mix is its extensive list of water- and fat-soluble vitamins, minerals, amino acids. Life Extension Mix provides enzymatically-active forms of B vitamins like pyridoxal-5-phosphate that provide immediate antiglycation benefits. This formula is the only multivitamin to contain 5-methyltetrahydrofolate (5-MTHF), the active form of folate that is more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic deficiency since it requires no conversion to become metabolically active.

Scientists have identified multiple mechanisms by which green tea extract helps protect against LDL oxidation, neuronal degradation, and a host of other structural and functional age-related changes. Life Extension Mix provides more green tea extract than found in commercial formulations.

Broccoli is one of the vegetables best documented to protect healthy DNA. The broccoli concentrate in Life Extension Mix is standardized to provide sulforaphane and other glucosinolates, compounds responsible for broccolis protective benefits.

Olive polyphenols help protect against LDL oxidation, quench free radicals, and stabilize cell membranes. Life Extension Mix contains an olive extract standardized to provide the best-documented polyphenol called hydroxytyrosol.

Luteolin is a flavonoid found in parsley, artichoke, basil, celery and other foods. It has shown the ability to help protect against DNA oxidative damage. When measured against 27 other citrus flavonoids, luteolin proved one of the most beneficial at maintaining healthy DNA. Luteolin also suppresses excess levels of interleukin-6 and interleukin-1b. Life Extension Mix contains a standardized dose of 8 mg of luteolin.

Lycopene is the red carotenoid in tomatoes that supports a healthy prostate and helps promote healthy lipid profiles for those already within a normal range. Lutein is found in spinach and collard greens and has been shown to help maintain eye macula pigment structure.

Pomegranate may be the most effective plant to help maintain optimal endothelial function. This pomegranate extract is standardized to provide the punicalagins and other polyphenols found in up to 2.6 ounces of pomegranate juice.

Sesame lignans increase tissue levels of vitamin E, including gamma tocopherol, and inhibit the formation of an inflammatory precursor called arachidonic acid.

The wild blueberry extract in Life Extension Mix is standardized to help maintain optimal neuronal function.

Bilberry extract has antioxidative properties that not only are neuroprotective, but help suppress photooxidative processes and have been shown to improve microcapillary circulation.

Cyanidin-3-glucoside is a berry compound that promotes healthy function of the retina to help support night vision.

Pterostilbene is a compound naturally found in blueberries and grapes that has been shown to have beneficial, anti-aging effects on gene expression and to promote healthy cognitive function.

D-glucarate is found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. D-glucarate supports a detoxification process that helps to remove DNA toxins.

Unlike folic acid, 5-MTHFwhich is more bioavailableis able to cross the blood-brain barrier. This is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain, the neurotransmitter associated with memory. It also better facilitates maintenance of healthy homocysteine levels.

Vitamin D3 helps maintain healthy bone density and DNA. There is five times more vitamin D in Life Extension Mix compared to conventional multivitamins.

Life Extension Mix utilizes natural mixed tocopherols that provide natural vitamin E from alpha tocopherol and a small amount of gamma tocopherol (40 mg). Compared to synthetic vitamin E, the natural form is far more bioavailable.

N-acetyl-L-cysteine suppresses free radicals inside the cell and maintains healthy glutathione levels. Taurine may protect against free radicals between cells and supports eye health.

Life Extension Mix contains the sodium selenite, selenomethionine, and Se-methyl L-selenocysteine forms of selenium. Some scientific evidence suggests that consumption of selenium may reduce the risk of certain forms of cancer; however, the FDA has determined that this evidence is limited and not conclusive.

Zinc is often poorly absorbed, but Life Extension Mix provides two of the most bioavailable forms of zinc.

Boron is not only needed to maintain healthy bone density but may also help promote healthy prostate cell function.

Life Extension Mix provides a high amount of an optimal form of chromium to help maintain arterial wall structure and already normal glucose levels.

Magnesium helps protect arteries and heart valves, and supports heart and brain cells. Life Extension Mix provides high potencies of six different forms of magnesium to fully saturate the body with this life-saving mineral.

Choline, phosphatidylcholine and inositol help maintain high levels of acetylcholine in the brain to support cognitive function and memory.

A healthy type of dietary fat, medium-chain triglycerides are easily absorbed intact and transported directly to the liver, where they are immediately used for energy.

Due to license restrictions, this product is not for sale to doctors and MLM wholesalers in the USA, Canada or the Philippines.

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Life Extension Mix Tablets, 315 tablets

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What Are Nootropics? A Guide to Nootropic Supplements

Posted: July 7, 2016 at 4:12 pm

Nootropics are a class of cognitive enhancing supplements that are used to improve concentration and boost memory power. Nootropics are often used to increase attention spans, help individuals focus and as studying aids.

You will occasionally see Nootropics referred to as smart drugs as they are associated with increased intelligence, motivation, and mental energy.

However, unlike smart drugs which can often cause negative side effects with long-term use, nootropics must be safe, neuroprotective and pose a very low risk of side effects when used appropriate.

Many nootropics share similar mechanisms of action by enhancing increased communication between neurons, helping to balance neurotransmitter levels or by promoting brain cell health. They may help improve energy metabolism in your neurons, support neuroplasticity, or even stimulate the growth of new neurons and synapses.

What are Nootropics and how do they really work? Which are the best nootropics to use if you are a new user?

This article will provide a basic guide to nootropics and give you an overview of how to use these supplements to enhance your mental capabilities.

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Nootropics are broadly any type of neuro enhancing drug or natural supplement with very low prevalence of side effects. The actual definition of what makes a supplement a nootropic is somewhat of a loose concept.

The original description comes from Belgian pharmacologists S. Giurgea and V. Skondia who invented the first Nootropic a compound known as Piracetam in 1963.

They established the classification of Nootropics to refer to cognitive boosting substances with extremely low toxicity that can be taken for long-term use.

This highlights the fact that Piracetam and other Nootropics are able to improve brain functions without any of the negative side effects associated with brain stimulants.

Piracetam (known also by the name Nootropil) is one of the best known Nootropics and makes up part of the Racetam family along with Aniracetam, Phenylpiracetam, Pramiracetam, Oxiracetam, Nefiracetam, Coluracetam and Nebracetam. These are all synthetic compounds that have been created in the lab, but there are also a number of effective herbal and natural nootropic supplements.

For example, fish oil, grape seed extract, bacopa monnieri, yerba mate and even licorice are all natural nootropics. (Click here to see a full Nootropics List of supplements that are available.) You will often find these supplements combined together in a Nootropic Stack to further enhance their effectiveness.

What exactly do Nootropics do? Like smart drugs, Nootropics will not instantaneously give you a higher IQ or a better intellect. But they may boost your brain functions by increasing the production and signalling of various neurotransmitters.

Your brain is essentially a network of billions of neurons connected by synapses. These neurons communicate and work together through chemicals known as neurotransmitters. When neurotransmitters are able to send signals more efficiently, you experience improved concentration, better memory, mood elevation, increased processing ability for mental work, and longer attention spans.

With continued supplementation of certain nootropics, you can improve the synaptic plasticity of neurons, causing long lasting improvement to the health and functioning of your brain.

Other nootropics show effects of vasodilation which means they increase the blood flow to your brain. This supplies your brain with more oxygen, nutrients, and glucose the primary energy source used by the brain during long periods of focus.

The brain requires an immense amount of energy to perform its function, sustain consciousness and to pay attention to your external environment. Even though the brain is only 2% of your bodyweight, it constitutes 20% of your energy expenditure.

Performing mental exercises, learning new things, concentrating on your work and staying alert during the day all burn a lot of energy. By raising bloodflow and oxygenation, you can immediately experience greater capacity for memory and focus.

Supplements that can improve the energy supply to your brain cells (like Acetyl L-Carnitine, Caffeine, Creatine, Ginkgo Biloba, or Vinpocetine) can all enhance focus, mental energy and clarity. This type of nootropic is especially favored among students for studying as their effects are felt immediately.

Nootropics can also show signs of neuro-preservation and neuro-protection. These compounds directly affect the levels of brain chemicals associated with slowing down the aging process. Some nootropics could in an increase in the production of Nerve Growth Factor and Brain-Derived Neurotrophic Factor to stimulate the growth of neurons and neurites while slowing down the rate of damage as well.

Over time, this could potentially slow down signs of aging like loss of memory and even counter the development of disorders like Alzheimers disease.

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Below is a list of some of the most popular and best nootropics that are available today. Each supplement with have its own unique mechanism of action that is distinct from other nootropics.

You can either select the supplement that best matches your needs or goals, or you can combine several nootropic compounds together in what is known as a stack. A stack simply involves any pairing of substances that enhance and complement each other when taken simultaneously.

Most of the pre-packaged brain boosters available will stack together several different herbal or synthetic nootropics like those listed below, but you can also buy the bulk raw powder and mix your own capsules to design a formula that is right for you.

Racetam: As mentioned previously, racetams are a class of nootropics including the widely used Piracetam, Aniracetam, Pramiracetam, and Oxiracetam.

They all share a similar chemical structure with a Pyrrolidone nucleus. Racetams work by dramatically increasing levels of neurotransmitters and other chemicals required for proper brain function like glutamate and acetylcholine.

They have been tested to improve cognitive function, prevent damage to brain cells from alcohol consumption and other factors, and to increase the communication between the two hemispheres of the brain.

Choline: Choline is frequently found in a nootropic stack with racetams like Piracetam and Aniracetam. Taking choline supplements will cause greater production of the acetylcholine neurotransmitter in the brain.

Since Racetams result in increased uptake and demand for acetylcholine, stacking choline with this nootropic will further enhance your results. Studies have shown that choline supplementation can improve performance on memory tests as well as social behavior. Choline also plays a key role in the production of phospholipids that are incorporated into brain cell membranes.

Pyritinol: Pyritinol has anti-oxidant effects for supporting the long-term health of the brain. But its primary benefit is aiding glucose uptake for periods of extended mental strain. If you are studying or working for a long period of time,
your brain will start to diminish its glucose (sugar) stores which are the primary way that the brain derives its energy.

Psychological studies have shown that continuing to refuel your brain with glucose will improve concentration and cognitive ability during extended periods of mental work. Supplementing Pyritinol aids further in glucose uptake so that your mental energy levels are higher.

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Vinpocetine: Vinpocetine has been shown as one of the most effective nootropics for improving brain blood flow. After taking Vinpocetine, the blood vessels dilate and are able to circulate more blood to the brain.

This causes a number of immediately noticeable effects such as concentration boosting, better mental agility, and higher energy levels and motivation.

There are many more nootropics available out there and different ones can assist you in improving your brain in various different ways. For a full Nootropics List, keep reading this website and check out our many Nootropic reviews.

Which nootropic supplement you pick is largely a matter of personal preference. You might want to check out the pre-made nootropic products like Alpha Brain or you might prefer to design your own stack by purchasing ingredients like Piracetam powder.

The health and capabilities of your brain are one of the most important determining factors in a happy and successful life, so whatever you pick you can rest assured that you are making a smart investment.

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What Are Nootropics? A Guide to Nootropic Supplements

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Oceania Cruises – Cruise Vacations & Cruise Deals | Mid-Sized …

Posted: July 3, 2016 at 12:22 pm

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On April 27, 2016, Sirena, the newest member of the Oceania Cruises fleet, was christened in Barcelona, Spain. Watch the event as it happened live, including opening remarks from Oceania Cruises President Jason Montague, Sirenas Godmother Claudine Ppin, the christening of the ship, and all the festivities!

Filled with a spectacular array of diverse and exotic destinations, your world awaits your discovery. There is simply no better way to explore it than aboard the elegant ships of Oceania Cruises. Our unique itineraries are wide-ranging, featuring the most fascinating destinations throughout the world. Regatta, Insignia, Nautica, Sirena, Marina and Riviera are all intimate and luxurious, with each calling on the worlds most desirable ports, from historic cities and modern meccas to seaside villages and faraway islands. On a voyage with Oceania Cruises, each day offers the rewarding opportunity to experience the history, culture and cuisine of a wondrous new destination.

Relax on board our luxurious ships and savor cuisine renowned as the finest at sea, rivaling even Michelin-starred restaurants ashore. Inspired by Master Chef Jacques Ppin, these culinary delights have always been a hallmark that distinguishes the Oceania Cruises experience from any other. Considering the uncompromising quality, perhaps the most remarkable aspect of an Oceania Cruises voyage is its incredible value. Lavish complimentary amenities abound, and there are never supplemental charges in any of the onboard restaurants. Value packages ensure that sipping a glass of vintage wine, surfing the Internet or enjoying a shore excursion is both convenient and affordable.

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Oceania Cruises – Cruise Vacations & Cruise Deals | Mid-Sized …

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